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Micturition Process

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Micturition

Excretion is the process of removal of chemical wastes( mainly nitrogenous wastes) from the body. It plays a vital role in maintaining the Homeostatic( steady-state) condition of the body and organs concerned with the formation, storage and elimination of Urine constitute are " excretory system " (the urinary system is more appropriate than the excretory system for the removal of nitrogenous wastes product).


Bladder voiding is another name for this action. Humans have two kidneys, two ureters, a urinary bladder, and a urethra as part of their excretory system.


The Urine is filtered by the kidneys and carried to the bladder via the ureters, where it is stored until it is expelled. The neurological system, as well as the muscles of the bladder and urethra, control the Micturition process. Before excreting pee, the urinary bladder can retain 350-400ml of Urine.


Micturition Meaning:

It's the process of discharging Urine from the urinary bladder along the urinary tract from the body.


What is Micturition?

Micturition is the process of discharging Urine from the human body. Human beings and animals have a specialized organ system for the discharge of Urine from the body. Urine is expelled from the urinary bladder through the urethra( in the penis in males, and directly in females) by the relaxing of the sphincter muscles located at the opening of the urinary bladder into the urethra under the impulse from the nervous system.  It also happens by relaxation of detrusor muscles after the voluntary relaxation of the sphincter muscles such a process is called Micturition.


Human beings and animals have an organized urinary system that consists of two kidneys ( right and left kidney located on either side of the backbone and protected by the last rib ), ureter, urinary bladder, sphincter muscles, and urethra.


Micturition is also known as the voiding phase of the bladder. It lasts for a short time, and as the bladder stretches, its firing rate increases and this increases the urge for urination and sometimes Micturition relaxation; thus it is sometimes called involuntary Micturition or involuntary urination.


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Physical Properties of Micturition

Urine has a yellowish color ( due to the presence of urochrome ), and also the color varies with different diets. A healthy human being urinates around 1 to 1.5 liters per day of Urine but also varies with various conditions. Urine has a pH scale value between 5 to 8, i.e. it is slightly acidic ( pH scale value = 6) protein diet makes it acidic while vegetable diet makes it alkaline and on standing the smell of Urine becomes strong, ammonium like due to bacterial activities otherwise faint smell and its specific gravity is 1.003 to 1.035


Chemical Composition of Urine

The normal human Urine consists of about 95% of water and 5% solid wastes dissolved in it. The percentage of solid waste may slightly vary according to the food taken and the time after taking food. Still, usually, these are approximately ( in grams per liter in Urine) as follows:

Organic (in g/L)

Inorganic (in g/L)

Urea 

2.3

Sodium Chloride

9.0

Creatinine

1.5

Potassium Chloride

2.5

Uric Acid

0.7

Ammonia

0.6

Others

2.6

Others 

2.5


Besides the normal constituents, the Urine may pass out specific hormones and also certain medicines like antibiotics and excess vitamins.


Micturition Process

The Micturition process is divided into two steps or phases:

  1. Resting or Filling Stage

The Urine contained in the urinary bladder ( it acts as the primary storage organ ) is a balloon-shaped, hollow, muscular organ. A healthy urinary bladder can hold up to 16 ounces of Urine for 2 to 5 hours easily, and there opening is tightly closed by sphincter muscles which also prevents the leakage of Urine from the urinary bladder, and sphincter muscles facilitate the center of Urine from the urinary bladder into ureter that allows the Urine to pass outside the body.


During this phase of the bladder, Urine travels from the kidneys to the bladder via the ureters. The ureters are narrow muscular tubes that stretch downhill from each kidney and obliquely enter the bladder.


The ureters' oblique placement in the bladder wall serves as an important function. The ureter's passage into the Urine bladder is protected by no sphincters or muscles. As a result of the oblique shape of the hole, Urine cannot re-enter the ureters. The detrusor muscle, the urinary bladder's main muscle, relaxes at the same moment, allowing the bladder to expand and accommodate more Urine.


  1. Voiding Stage

Both the urinary bladder and the urethra are involved during this stage. Whenever the Urine is filled in the urinary bladder, it triggers the muscles and nerves, which in turn stimulates the need for urination, and the brain signals the urinary bladder to contract. The responses sent to the central nervous system by nerves in the urinary bladder encouraged by the filling of Urine in the urinary bladder and the answer sent back by the central nervous system to nerves in the urinary bladder signals the incitement of the contraction of the urinary bladder. Through the opening of the urinary bladder into the ureter and the Urine is eliminated and the process is called Micturition, and the neural mechanism involved is called the Micturition reflex.


The internal and external urethral sphincters are two muscles that govern the urethra. The internal sphincter is made up of smooth muscles, whereas the external sphincter is made up of skeletal muscles. During the filling stage, both of these sphincters are contracted.


Potential Problems of Micturition

Disturbances of the bladder's storage function and disturbances of the bladder's emptying function are the two types of Micturition disorders. Frequency, urgency, and incontinence are the most common signs of storage function problems. There are many diseases related to the Micturition process, and some of them are due to physical trauma or another physiological illness, and urination problems include initiating urination and bladder impairing bladder encrypting and urination inconvenience. A few of the diseased mentioned :


  • Detrusor Instability

It is a problem caused by which detrusor muscles contract without any reason. The muscles are responsible for the contraction of the urinary bladder and help in the processes of Micturition thus resulting is that it causes urination inconvenience.


In neurologically normal patients, detrusor instability is a common cause of urgency and urge incontinence. While the patient is striving to suppress Micturition, an involuntary phasic detrusor contraction of any pressure linked with urge or leakage is characterized.


  • Urinary Retention

It is a problem in which the inability to urinate completely occurs and the onset may occur suddenly or gradually, and the cause can be urethra blockage nerve problem and weak bladder muscles.


Your bladder does not empty entirely or at all when you urinate. Urinary retention is the medical term for this condition. Urinary retention is classified as either acute (sudden) or chronic (long-term) (long-term). Acute refers to something that happens quickly and can be dangerous. You've had chronic Urine retention for a long time if you have it.


  • Spinal Cord Trauma 

Urinary incontinence or overactivity of the bladder can be caused by spinal cord injuries, particularly those to the tenth thoracic vertebra (T10).


Stroke, Alzheimer's disease, and other conditions in which nerve pathways to and from the spine and brain are blocked or injured are examples of neurological disorders. Acetylcholine (ACh), a neurotransmitter, is involved in the relaying of nerve signals during Micturition. ACh can be blocked with the drug atropine, causing the detrusor muscle to contract and Urine retention.


Incontinence due to stress can occur at any age. It happens when the abdominal pressure rises, such as when sneezing or coughing. When abdominal pressure rises slightly, the normally acute angle between the bladder and urethra is lost, causing pressure in the bladder to rise.


Incontinence occurs as a result of muscle laxity and weakness at the bladder neck, around the urethra, and in the pelvic floor, with relatively minor pressure changes. Stress incontinence can occur in men after a prostatectomy, as well as in women after childbirth and during menopause due to reduced oestrogen secretions (McLaren, 1996).


Urine flow can be obstructed by renal stones, inflammation, or an enlarged prostate gland, resulting in frequent Micturition and Urine retention. Bladder tumours and pregnancy both reduce normal bladder capacity.


Micturition Problem Management

  • The factors in the environment that inhibit the Micturition should be absent. 

  • For a normal Micturition the coordination of the parasympathetic,  sympathetic, and somatic nerve as they help in the Micturition process

  • The capacity of the bladder to hold Urine should remain the same and regular.

  • Sphincters, detrusor, and pelvic muscles should have normal muscle tone and functioning.

  • In any region of the urinary bladder and urinary tract, there should be no obstruction.


Key Points in Micturition

  • Urine is created and collected in nephron or uriniferous tubule (in the kidney) and flows into the ureter

  • Ureter  muscle facilitation of the smooth muscle contraction

  • The Urine is stored in a hollow, elastic, and muscular organ of the urinary bladder

  • The Urine flows out through the urethra

  • The Urine carries out waste from the body(mainly nitrogenous wastes if stored in the body may be very harmful and may even cause death )

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FAQs on Micturition Process

1. What causes the Micturition reflex to be triggered?

Micturition is divided into two phases: storage and voiding. The firing rate of stretch receptors in the bladder increases as the bladder fills up. The Micturition reflex is triggered, which increases Urine urge and can result in involuntary urinating.

2. Do the kidneys filter the blood for wastes?

To create Urine, a healthy kidney filters around half a cup of blood, eliminating wastes and extra water. The ureters, two narrow muscular tubes on either side of the bladder, transfer Urine from the kidneys to the bladder.

3. Does nervousness make Micturition more difficult?

When we're stressed, our fight-or-flight response activates, generating the release of hormones that disrupt the bladder's regular hormone balance and cause it to contract. As a result, people may feel forced to urinate or, in rare cases, urinate involuntarily.

4. Is it possible to treat a neurogenic bladder?

While neurogenic bladder cannot always be cured, it can almost always be treated. The majority of cases of neurogenic bladder can be treated with medication and intermittent catheterization. Only a small fraction of children who get this condition will require extensive reconstructive surgery.

5. Define the Process of Micturition?

It's the process of discharging Urine from the urinary bladder along the urinary tract from the body.

6. Mention any Three Disorders of Micturition Which Causes Urinary Incontinence?

Three disorders of the Micturition are :

  • Detrusor instability
  • Urinary Retention
  • Spinal cord trauma

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