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Pituitary Gland

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The pituitary gland is a brain-based endocrine gland. It creates hormone-like substances which are chemical messengers that help organs communicate.


The endocrine system includes the pituitary gland. By releasing hormones into your bloodstream, the pituitary gland aids in the control of your body's processes. These hormones go through your bloodstream to their intended destination.


They usually cause the release of the second hormone in this situation. The target can be specialised endocrine glands or other types of body tissue, such as cell groups.


Because it regulates several other hormone-releasing glands, the pituitary gland is sometimes referred to as the master gland. The pituitary gland regulates several glands, including the thyroid, ovaries, testicles (testes), and adrenal glands.


Pituitary Gland - Function and Disorders

Function

The thyroid gland, adrenal gland, ovaries, and testicles are all controlled by the master gland. While it controls these glands, it receives orders from its neighbour, the hypothalamus.


The pituitary gland produces hormones that tell the glands how much hormone they should produce.


The pituitary gland also manufactures hormones for the body's organs like:

  • Oxytocin stimulates contractions in the uterus and mammary glands, which in turn aid in childbirth and milk production.

  • Vasopressin is an antidiuretic hormone that helps the kidneys function properly.

  • A beta-melanocyte-stimulating hormone is a hormone that causes the skin to darken.

  • Endorphins are neurotransmitters that help the brain and immune system reduce pain and control the immune system.

  • Hormones that promote muscle and bone growth.

  • Enkephalins are pain-blocking brain chemicals.


Most hormones are released every one to three hours, following the body's circadian rhythm. Hormone production peaks throughout the day and declines at night. 


Disorders

Pituitary disorders are caused by the pituitary gland being either excessively active or inactive. An isolated portion of the pituitary gland, known as a pituitary adenoma, frequently causes complications (if it is large it may be called pituitary macroadenoma). 

These tumours are normally benign and non-cancerous. Adenomas of the pituitary gland can create issues by:

  • Excess of one or more hormones is released.

  • Not producing hormones but pressing on normal pituitary tissue, causing the normal function to be disrupted; and/or

  • Putting pressure on surrounding structures, such as the eye's nerve, results in blurred vision or the loss of a portion of eyesight.

The pituitary gland produces too much of one or more of its hormones in the following conditions:

  • Acromegaly

  • Cushing's syndrome

  • Prolactinoma

The pituitary gland produces insufficient hormones in the following conditions:

  • When adult growth hormones are deficient.

  • Diabetes insipidus which is a kind of diabetes that affects the kidneys.

  • Hypopituitarism.

  • Tumours of the pituitary gland.

  • Hypothalamic tumours or injuries that have a knock-on impact on the pituitary gland.

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FAQs on Pituitary Gland

1. Why is the Pituitary Gland Called the Master Gland? 

As per the pituitary gland definition, it is known to be the master gland because of its responsibility for secreting most hormones needed to regulate various body functions. 

2. What are Some Hormones that Anterior Pituitary Gland Secretes? 

Anterior parts of the pituitary gland secrete various kinds of hormones such as growth hormone, prolactin, thyroid-stimulating hormone, beta melanocyte-stimulating hormone, and endorphins, etc. 

3. Where is a Pituitary Gland Situated? 

Pituitary gland is located inside a bony structure named sella turcica present at the base of the brain. It is under the brain and right behind the bridge of the nose and is divided into two parts – anterior lobe and posterior lobe. 

4. How are pituitary disorders identified?

Hormone blood tests and brain imaging are frequently used to make the diagnosis. Some hormone blood tests can be done at random, but others may require specialised testing with drugs that should cause or inhibit release in specific circumstances. 


This may necessitate admission to a day unit and the administration of many hormone blood tests throughout the day. An MRI scan of the pituitary gland is usually performed to check for pituitary abnormalities, such as adenoma or cysts.

5. What are the options for treating pituitary disorders?

This will be determined by the cause. If there is a hormone shortage, it may be necessary to supplement with tablets. If a tumour is found to be the source of the issues, pituitary surgery may be necessary. 


This is commonly done through the nose. If a pituitary tumour is confirmed to be malignant, radiation may be required following surgery. Following any treatment, hormone replacement may be required for the rest of your life.

6. What are the parts of the pituitary gland?

The pituitary gland is pea-sized. It is positioned near the brain's base, behind the bridge of the nose. The pituitary gland is located near the hypothalamus, which is a component of the brain.

The pituitary gland has two parts:

  • The anterior pituitary gland is the section of the pituitary gland that is located in the front of the brain.

  • The posterior pituitary gland is the section of the pituitary gland that is located at the back of the head.

Different hormones are released by these two components, each focused at a different portion of the body.

7. What are the names and the most important hormones made by Pituitary gland?

Several hormones are produced by the pituitary gland. Among them the most important are:

  • ADH is an adrenal hormone that stimulates the adrenal glands (glands located above or on top of the kidneys that produce hormones). An ACTH injection causes the adrenal glands to release the stress hormone cortisol.

  • Thyroid-stimulating hormone (TSH) promotes thyroid hormone synthesis and secretion (a gland in the hormone system). It regulates metabolism and is vital for growth.

  • FSH and LH are hormones that regulate male and female sexual function. Gonadotropins are LH and FSH. They stimulate the ovaries to produce oestrogen and the testes to produce testosterone.

  • Growth hormone (GH) promotes appropriate bone and tissue growth.

  • Antidiuretic hormone (ADH) regulates renal water loss.

8. What are the natural ways to boost Human Growth Hormone (HGH) naturally?

  • The most hazardous sort of stored fat is belly fat, which has been related to a variety of ailments. HGH levels and other elements of your health will benefit from losing abdominal fat.

  • Intermittent fasting can help you get the most out of your HGH. It can help you lose body fat, which has a direct impact on HGH synthesis, as well as maintain your insulin levels low for the majority of the day.

  • Lessening your diet of refined carbs and sugar may assist in optimising growth hormone levels.

  • Because most meals produce an increase in insulin levels, several doctors recommend avoiding eating right before bedtime.


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