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Streptomycin

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Streptomycin Antibiotic

MVSAT 2024

Streptomycin is known to be an antibiotic that is used to treat bacterial infections such as tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. Streptomycin is an antibiotic that is produced by the soil organism Streptomyces griseus. Selman Waksman, Albert Schatz, and Elizabeth Bugie, three American biochemists, discovered streptomycin in 1943. The drug works by interfering with a microorganism's ability to synthesise certain essential proteins.


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It was the first antimicrobial agent discovered after penicillin and the first antibiotic effective against tuberculosis. Streptomycin was widely used because it was effective against a wide range of diseases; as a result, many initially sensitive microorganisms, including the bacterium that causes tuberculosis, developed resistance to the antibiotic. It is used in conjunction with penicillin to treat infections of heart valves (endocarditis), and it is used in conjunction with tetracyclines to treat plague, tularemia, and brucellosis.


Streptomycin Medicine Uses

This medication is used in conjunction with various other medications to treat active tuberculosis (that is also known as TB) infection, if you are unable to take other TB medications or if you have a type of TB that cannot be treated with other medications (drug-resistant TB). Streptomycin is an aminoglycoside antibiotic, which is a type of antibiotic. It kills the organisms that cause the infection. Along with other medications, this streptomycin drug may be used to treat other serious infections (e.g., Mycobacterium avium complex-MAC, tularemia, endocarditis, plague).


Streptomycin Tuberculosis

Streptomycin is also used for tuberculosis treatment when one or more of the preceding drugs is contraindicated due to toxicity or intolerance. As a result of rising rates of drug resistance and concurrent HIV infection, tuberculosis management has become more complicated.

Streptomycin is an aminoglycoside antibiotic derived from Streptomyces griseus that is used to treat tuberculosis and other Gram-negative infections.

Medication for tuberculosis is typically taken for 9 months or longer. After taking streptomycin on a daily basis for 1 to 2 months, your doctor may advise you to take it less frequently (e.g., 2 to 3 times a week).


Penicillin and Streptomycin

Alexander Fleming discovered that mould from the genus Penicillium inhibited the growth of bacteria in 1928. This unknown antibacterial substance was dubbed penicillin by Fleming. Ten years later, a group of researchers at Oxford University began studying penicillin in laboratory mice. During World War II, penicillin was hailed as a miracle drug that saved countless lives.

Penicillin antibiotics are available as

  • tablets,

  • capsules,

  • powder for oral suspension, and

  • powder for injection.

Penicillin antibiotics prevent bacteria from multiplying by preventing the formation of the walls that surround them. The walls protect the bacteria from their surroundings and keep the contents of the bacterial cell together. Bacteria cannot survive in the absence of a cell wall. When bacteria are actively multiplying and forming cell walls, penicillin antibiotics are most effective.

Penicillin is a common antibiotic used to treat bacterial infections caused by staphylococci and streptococci. Penicillin is a member of the beta-lactam antibiotic family, which uses a similar mechanism of action to inhibit bacterial cell growth, eventually killing the bacteria.


Streptomycin Price

The average price for 1 Solution Reconstituted, 1gm is \[\$\]100.89. By using the WebMDRx coupon, you can purchase streptomycin sulphate for \[\$\]85.00, a 16 percent savings. Even if this medication is covered by Medicare or your insurance, we recommend that you shop around for the best price.


Streptomycin Side-Effects

Nausea, vomiting, stomach upset, or loss of appetite are all possible side effects. The injection site may experience pain, irritation, or redness. Inform your doctor or pharmacist right away if any of these side effects persist or worsen.

Remember that your doctor prescribed this medication because he or she believes the benefit to you outweighs the risk of side effects. Many people who take this medication do not experience serious side effects.

Notify your doctor right away if you experience any serious side effects, such as muscle weakness, persistent diarrhoea even after discontinuing this medication, easy bleeding/bruising, rapid heartbeat, new signs of infection (e.g., high fever, persistent cough), signs of kidney problems (such as a change in urine volume), or unusual tiredness.

Long-term or repeated use of this medication may result in oral thrush or a new vaginal yeast infection. If you notice white patches in your mouth, a change in vaginal discharge, or any other new symptoms, consult your doctor.


Streptomycin Treatment

This medication is used in conjunction with various other medications to treat active tuberculosis (TB) infection if you are unable to take other TB medications or if you have a type of TB that cannot be treated with other medications (drug-resistant TB). Streptomycin is an aminoglycoside antibiotic, which is a type of antibiotic.


Spectinomycin Streptomycin

In some cases, spectinomycin can be used instead of streptomycin because it is more stable; however, when increased stability is not required, streptomycin should be used because it is much more cost-effective.

Streptomycin is an aminoglycoside antibiotic. It kills bacteria by inhibiting the ability of 30S ribosomal subunits to produce proteins. Streptomycin was isolated from Streptomyces griseus by Albert Schatz in 1943. Streptomycin is on the WHO's List of Essential Medicines.


Hormone Streptomycin

Streptomycin is an aminoglycoside antibiotic, which is a type of antibiotic. It kills the organisms that cause the infection.

Along with other medications, this drug may be used to treat other serious infections (e.g., Mycobacterium avium complex -MAC, tularemia, endocarditis, plague).

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FAQs on Streptomycin

1. Why is Streptomycin So Effective?

Answer. Streptomycin is a powerful antibiotic because its structure is similar to that of anticodons, which normally bind to the ribosome. Streptomycin is significant because it was the first antibiotic capable of curing tuberculosis. Bacteria have developed resistance to streptomycin over time.

2. Why is Streptomycin Not Given Orally?

Answer. Humans and bacteria have structurally different ribosomes, allowing this antibiotic to be selective for bacteria. Streptomycin cannot be taken orally and must be administered intramuscularly on a regular basis. Ototoxicity is a side effect of this medication. It has the potential to cause permanent hearing loss.


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