1. In Which of the Following Substances is Chlortetracycline Soluble:
(a) Water
(b) Ether
(c) Organic solvents
(d) All of the above
Answer: Water
2. Cell-wall Biosynthesis is Inhibited by Antibiotics by Inhibiting the Biosynthesis of Which of the Following?
a) lipopolysaccharide
b) cellulose
c) peptidoglycan
d) proteins
Answer: Peptidoglycan
3. Bacterial Cells Grown in a Medium Exposed to High Osmotic Pressure, Changes Shape from Rod-shaped to __________ Shaped.
a) spherical
b) rod shaped
c) irregular
d) elongated
Answer: Spherical
4. Which Among of the Following Antibiotics Act as Folate Antagonist:
a) Penicillin
b) Tetracycline
c) Trimethoprim
d) Cefotaxime
Answer: Trimethoprim
5. Which Among the Following Antibiotics Function as Protein Synthesis Inhibitors:
a) Penicillin
b) Tetracycline
c) Cefotaxime
d) Trimethoprim
Answer: Tetracycline
6. At Normal the pH Value of Penicillin Remains in Which Form:
a) Solvent phase
b) Precipitates
c) Aqueous phase
d) Both (a) and (b)
Answer: Aqueous phase
7. Which of the Following Antibiotics Functions as Cell Wall Inhibitors:
a) Penicillin
b) tetracycline
c) trimethoprim
d) Ciprofloxacin
e) Cefotaxime
Both a and e
a, c and d
c, d and e
All of the above
Answer: a and e
8. Which of the Following Antibiotics is Effective in treatingoral Candidiasis:
a) Nystatin
b) Bacitracin
c) Tetracycline
d) Griseofulvin
Answer: Nystatin
9. In Which of the Following Substances is Chlortetracycline Soluble:
a) Water
b) Ether
c) Organic solvents
d) All of the above
Answer: Water
10. The Crystalline Sodium or Potassium Salts are Slightly Soluble in:
a) ether
b) dioxane
c) water
d) chloroform
Answer: Chloroform
11. Which of the Following Antibiotics is Most Likely to Cause Depression of the Bone Marrow:
a) Streptomycin
b) PencillinG
c) Tetracycline
d) Trimethoprim
e) Amphotericin B
Answer: Amphotericin B
12. Which of the Following Does not Affect the Activity of Penicillin?
a) Bile
b) Hydrochloric acid
c) Cysteine
d) Sodium hydroxide
Answer: Bile
13. Benzylpenicillin is the Chemical Name for Which of the Following Penicillin?
a) Penicillin G
b) Penicillin V
c) Penicillin F
d) Phenethicillin
Answer: Penicillin G
14. Which of the Following Does not Affect the Activity of Penicillin?
a) Bile
b) Hydrochloric acid
c) Cysteine
d) Sodium hydroxide
Answer: Bile
15. Streptomyces Orientalis Produces Which of the Following Antibiotics?
a) Cephalosporins
b) Cycloserine
c) Bacitracin
d) Vancomycin
Answer: Vancomycin
16. Which of the Following Fermentation Processes is Used in the Production of Penicillin?
(a) Aerobic fermentation followed by anaerobic fermentation
(b) Anaerobic fermentation
(c) Aerobic fermentation
(d) Anaerobic fermentation followed by aerobic fermentation
Answer: Aerobic fermentation
17. Which of the Following Interferes with the Regeneration of the Monophosphate Form of Bactoprenol from the Pyrophosphate Form?
a) Vancomycin
b) Ampicillin
c) Bacitracin
d) Cephalosporins
Answer: Bacitracin
18. After the Fermentation Process, Penicillin is Recovered as
a) Penicillin
b) Sodium penicillin
c) Calcium penicillin
d) Potassium penicillin
Answer: Potassium penicillin
19. Streptomycin is Produced by Which of the Following Organisms?
a) Streptomyces noursei
b) Streptomyces nodosus
c) Streptomyces fradiae
d) Streptomyces griseus
Answer: Streptomyces griseus
20. Tyrocidines are More Effective Against Which Organism:
a) Gram-positive organisms
b) Gram-negative organisms
c) Mycoplasmas
d) Spirochetes
Answer: Gram-positive organisms
21. Multiple Drug Resistance is Most Closely Related to Which of the Following:Â
a) Plasmids
b) Viruses
c) Transformation
d) Cell chromosome
Answer: Plasmids
22. Which of the Following Penicillin has Bes Gram Negative Spectrum:
a) Nafcillin
b) Ampicillin
c) Methicillin
d) Penicillin V
Answer: Ampicillin
23. Cell-wall Biosynthesis is Inhibited by Antibiotics by Inhibiting the Biosynthesis of Which of the Following?
a) Lipopolysaccharide
b) Cellulose
c) Peptidoglycan
d) Proteins
Answer: Peptidoglycan
24. What is the Typical Drug of Choice for Most Orofacial Infection:
a)Â Penicillin
b) tetracycline
c) trimethoprim
d) Ciprofloxacin
Answer: Penicillin
25. The High Yield of Chlortetracycline Requires Which Among the Following:
(a) No aeration
(b) Controlled aeration
(c) Continuous aeration
(d) Aeration which does not affect the yield
Answer: Continuous aeration
26. Which of the Following Interferes with the Regeneration of the Monophosphate Form of Bactoprenol from the Pyrophosphate Form:
a) Vancomycin
b) Ampicillin
c) Bacitracin
d) Cephalosporins
Answer: Bacitracin
27. Streptomycin is Produced by Which of the Following Organisms?
a) Streptomyces noursei
b) Streptomyces nodosus
c) Streptomyces fradiae
d) Streptomyces griseus
Answer: Streptomyces noursei
28. Tyrocidines are More Effective Against:
a) Gram-positive organisms
b) Gram-negative organisms
c) Mycoplasmas
d) Spirochetes
Answer: Gram-positive organisms
29. Which of the Following Events Occurs During the Second Phase of Growth of Penicillium Chrysogenum?
(a) pH increase
(b) Mycelial mass increases
(c) Both (a) and (b)
(d) Synthesis of penicillin is high
Answer: Both (a) and (b)
30. Streptomycin is Produced by Which of the Following Organisms?
a) Streptomyces noursei
b) Streptomyces nodosus
c) Streptomyces fradiae
d) Streptomyces griseus
Answer: Streptomyces griseus
31. Which of the Following Statements are True about Penicillin at Acidic pH?
a) Penicillin precipitates
b) Penicillin remains in the aqueous phase
c) Penicillin remains in the solvent phase
d) None of the above
Answer: At acidic pH penicillin remains in the solvent phase.
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