Have you ever wondered how the food we eat is circulated around the whole body? Or when we take medicine or get an injection, how are they circulated to the part that needs them? The answer to the above questions is the lymphatic circulatory system. It is a subsystem of the circulatory system and is composed of tissues and organs. It is also known as the lymphoid system and is an essential component of the immune system. Below we will learn more about the lymphatic system.
This system is present in the body of vertebrates and is composed of vessels, tissues, and organs. The human lymphatic system helps in maintaining fluid balance. It does so by collecting the excess fluid from tissues and then deposits it into the bloodstream. The lymph circulatory system also generates lymphocytes that help in fighting against the diseases. The fluid that runs through the lymphatic system is known as lymphatic fluid.
The lymphatic system in the human body is made up of lymph, lymphatic vessels, lymphatic nodes, and lymphoid tissue. Lymph is a colourless, watery fluid that mainly consists of white blood cells and is carried by the lymphatic system. The lymph vessels are the site of fluid drainage. They pump the lymph fluid with the help of skeletal and smooth muscles. To prevent the backflow the larger lymph vessels are present with valves. A lymph node is nothing but a mere collection of lymphoid tissue. They are located at regular intervals in the lymphatic system. Lymphoid tissue is composed of lymphocytes along with other specialized cells and tissues that help in maintaining the immune system functions. The lymphatic system diagram is shown below.
[ Figure: The lymphatic system in humans]
After reading the above information you must be thinking about that where does lymph drain? Well, the answer to this question will be covered under this topic. The lymphatic system can be thought of as a drainage system that is needed by the body because blood circulates and its plasma is leaked into the thin walls of the capillaries. Extracellular fluid is the portion of the blood plasma that escapes and it contains oxygen, amino acid, and other useful nutrients that are needed by the body and tissue cells. Almost all of the fluid gets back into the bloodstream but a small percentage of it along with the particulate matter is left behind. Here then comes the role of the lymphatic system which helps in removing these fluids and materials from tissues which thus prevents the fluid imbalance in the body. This imbalance can lead to the death of the organism. This lymph gets drained into larger vessels that are known as lymphatic vessels and these vessels converge to form the lymphatic trunk. These lymphatic trunks are connected to the veins and thus the excess materials or the infectious microorganisms are removed via this pathway. These lymphatic vessels are punctuated at intervals by small masses of lymph tissue which are known as lymph nodes.
The body lymph system is divided into primary lymphoid organs and secondary lymphoid organs. The primary lymphoid organs are the sites of B and T cells maturation sites and the secondary lymphoid organs are where these cells are further differentiated and perform their functions. Thymus, bone marrow, fetal liver are the primary lymphoid organs. Thymus and bone marrow are the major key players in immune function. The cells that mature in the bone marrow are termed B cells and the cells that migrate from bone marrow to thymus are called T cells. When these B and T cells mature they are migrated to the secondary lymphoid organs via the bloodstream where they are activated by coming in contact with the foreign materials which are termed as antigen. Lymph nodes, spleen, tonsils are termed secondary lymphoid organs. This is where these matured cells perform their function.
1. Explain the Lymphatic System associated with Diseases.
Answer: The primary lymphoid organs are of great importance to us. Two autoimmune diseases, DiGeorge syndrome and Nezelof disease are caused when the thymus fails to develop T cells which ultimately causes the reduction in their number and the immunity of the organism is compromised. Als if the bone marrow is not functioning well then it has devastating effects on the immune system because it plays a major role in B cell development and is also a source of stem cells.
2. Describe the role of the Lymphatic System in Human Beings.
Answer: As we studied above the primary role of the lymphatic system is to return the proteins and fluid to the blood. Via this process, the lymph nodes get swelled up because the bacteria, allergic particles and cancerous cells get collected in the lymph nodes which further stimulate lymphocyte proliferation and thus enlarging the lymph nodes. It protects our body from illness-causing invaders and also maintains body fluid levels. It also absorbs digestive tract fats and helps in removing cellular waste. The lymphatic system is thus important for the optimal functioning of our immune system.