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Hemozoin is a toxic substance formed in case of malaria. It is produced by
A. Globin protein of RBC
B. Colour pigment of RBC
C. Dead V Dn
D. Crypto zoites

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Last updated date: 25th Jul 2024
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Answer
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Hint: Hemozoin is a crystalline, brown pigment shaped and sequestered in Plasmodium's digestive vacuole as a byproduct of haemoglobin (Hb) catabolism. The parasite digests up to $80\%$ of the Hb in the host RBC, which it then uses as a source of nutrients and energy.

Complete answer:
Hemozoin is a waste product produced by the digestion of blood in certain blood-feeding parasites such as malaria parasites. Hemozoin is a biocrystal produced by Plasmodium and other blood-feeding parasites to escape the toxicity of free heme extracted from haemoglobin digestion during erythrocyte invasion.
They digest haemoglobin and produce a large amount of free heme, which is the non-protein portion of haemoglobin and a prosthetic group consisting of an iron atom in the centre of a porphyrin ring. Since free heme is toxic to cells, parasites transform it to an insoluble crystalline form known as hemozoin.
Two hosts are involved in the life cycle of the malaria parasite. During a blood meal, a malaria-infected female Anopheles mosquito inoculates the human host with sporozoites. Sporozoites invade liver cells, grow into schizonts, and rupture, releasing merozoites.

Hence the correct answer is option B) Colour pigment of RBC.

Note:
The presence of malarial pigment, or hemozoin, is a distinguishing feature of infected red blood cells.Malaria is an infectious disease spread by mosquitoes that affects humans and other species. Malaria signs usually include fever, exhaustion, vomiting, and headaches.