
Hemozoin formed in malaria is produced from
A. Globin part of haemoglobin
B. Haem of haemoglobin
C. Cryptozoite
D. Dead leukocytes
Answer
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Hint: Malaria is caused by a parasite called Plasmodium, which is usually transmitted by infected mosquitoes. Malaria severity varies according to Plasmodium species. Chills, fever, and sweating are common symptoms that appear a few weeks after being bitten.
Complete answer:
Two hosts are involved in the life cycle of the malaria parasite. During a blood meal, a malaria-infected female Anopheles mosquito inoculates the human host with sporozoites. Sporozoites invade liver cells, grow into schizonts, and rupture, releasing merozoites.
The presence of malarial pigment, or hemozoin, is a distinguishing feature of malaria-infected red blood cells. Hemozoin is a biocrystal synthesised by Plasmodium and other blood-feeding parasites to prevent the toxicity of free heme resulting from haemoglobin digestion during erythrocyte invasion.
Hemozoin is an iron-containing pigment that accumulates in malaria parasites as cytoplasmic granules. It is made up of the heme portion of haemoglobin (from human RBC) that the malarial parasites consume as they invade the RBC. Since the free heme is poisonous to the parasite, it converts it to hemozoin.
So, option B is the correct answer Haem of haemoglobin.
Note:
Two hosts are involved in the life cycle of the malaria parasite. During a blood meal, a malaria-infected female Anopheles mosquito inoculates the human host with sporozoites. Sporozoites invade liver cells, grow into schizonts, and rupture, releasing merozoites.
Complete answer:
Two hosts are involved in the life cycle of the malaria parasite. During a blood meal, a malaria-infected female Anopheles mosquito inoculates the human host with sporozoites. Sporozoites invade liver cells, grow into schizonts, and rupture, releasing merozoites.
The presence of malarial pigment, or hemozoin, is a distinguishing feature of malaria-infected red blood cells. Hemozoin is a biocrystal synthesised by Plasmodium and other blood-feeding parasites to prevent the toxicity of free heme resulting from haemoglobin digestion during erythrocyte invasion.
Hemozoin is an iron-containing pigment that accumulates in malaria parasites as cytoplasmic granules. It is made up of the heme portion of haemoglobin (from human RBC) that the malarial parasites consume as they invade the RBC. Since the free heme is poisonous to the parasite, it converts it to hemozoin.
So, option B is the correct answer Haem of haemoglobin.
Note:
Two hosts are involved in the life cycle of the malaria parasite. During a blood meal, a malaria-infected female Anopheles mosquito inoculates the human host with sporozoites. Sporozoites invade liver cells, grow into schizonts, and rupture, releasing merozoites.
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