Courses
Courses for Kids
Free study material
Offline Centres
More
Store Icon
Store

Which of the given statement(s) about N, O, P, Q with respect to M is/are correct?

A.M and N are non-mirror image stereoisomers.
B.M and O are identical
C.M and P are enantiomers
D.M and Q are identical

seo-qna
Last updated date: 22nd Jun 2024
Total views: 54.3k
Views today: 0.54k
Answer
VerifiedVerified
54.3k+ views
Hint: Stereoisomers are divided into enantiomers and diastereomers. Enantiomers are mirror images and diastereomers are not mirror images but both are non-superimposable with chiral centres. Identical molecules differ from each other only in the spatial orientation of groups in the molecule.

Complete Step-by-Step answer:
Two different molecules are said to be enantiomers if they are non-superimposable mirror images of each other. They have same refractive index, density, boiling and melting points but different direction of rotation in the polarimeter. They interact in different manner with other chiral molecules and are difficult to separate. Enantiomers differ in their configuration such as R or S at the stereogenic centre. We already know that these configurations are assigned by the Cahn-Ingold-Prelog (CIP) rules.
Diastereomers are the non-superimposable non-mirror images but have two or more chiral centres. When four different groups are attached to an asymmetric carbon atom, it is a chiral molecule. They are easy to separate as they have different melting and boiling points. For example, geometric isomers such as cis/trans.
To convert into enantiomers, both chiral carbon atoms must change their configuration. All stereocenters must be different for molecules to be enantiomers. And to convert into diastereomers, only one chiral carbon atom must change configuration. This is an important condition that at least one stereocenter must be different and at least one stereocenter must be same for molecules so as to be diastereomers.
Identical molecules are those two molecules that can be superimposed on each other, through rotation of bonds i.e. conformational changes or via rotation of the molecule itself. These are considered to be the same molecule or identical twins. They differ from each other only in the spatial orientation of groups in the molecule.
Let us write all the given molecules in Fischer projection from sawhorse projections and write the configurations of each chiral carbon as per CIP rules.

From these configurations we can easily see that M and N are diastereomers as they have different configuration at one chiral carbon and same at another chiral centre. therefore, M and N are non-mirror image stereoisomers. So, option (A) is correct.
Let us look at option (B), M and O are identical. Yes, we can clearly see that both the molecules look identical. The position of every atom and configuration of each chiral carbon is same in both. So it is a correct option.
In option (C), it is stated that M and P are enantiomers. We can see that the configurations are opposite at each chiral carbon in the two molecules. This is the case of enantiomers in which both chiral carbon atoms must change their configuration. So, this option is also correct.
In the last option, it is mentioned that M and Q are identical but they are not because the configurations are changed and not same. So, this option is incorrect.
Hence, the correct options are (A), (B) and (C).

Note: Point to be noted here is all molecules are not identical on rotation of a single bond. There exist conformers showing conformational isomers. Conformational isomerism is a type of stereoisomerism in which isomers can only be converted by formally single bond rotations. Also, all enantiomers are known to be optically active.