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Suicidal Bags of Cell

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What Are The Suicidal Bags Of Cell?

A cell is a basic unit and the building block of a living organism. These are the smallest units of life. There are unicellular as well as multicellular organisms in the world. Cells are responsible for energy production in our bodies. Every cell organelle carries out a special function for our body. Lysosomes are the cell organelles that are known as the suicidal bags of cells.


Types Of Cells In The Human Body

There are four main types of cells in the human body, as listed below.

Epithelial Cells: Our skin is made up of epithelial cells. Different organs in our body are made up of different epithelial cells. They cover our interior hollow organs like the oesophagus, blood vessels, stomach, etc. These cells protect our bodies and organs from external shocks.

Nerve Cells: These cells are very important for communication. They provide a channel between our brain and the different organ systems. They play an important role in our body function. They receive and transmit the sensory information from our brain and send it to the designated part of the body like muscles, eyes, ears.

Muscle Cells: They are specialized cells mainly responsible for contraction and expansion purposes. Without these cells, a person can't do a single movement. There are three types of muscle cells in the body, and they all function together. These also form a protective cover in organs and protect them from shock and internal injury. The contraction and expansion control the diameter of the hollow organ.

Connective Tissue Cells: They provide structural strength to the body and also defend from foreign invaders. Fibroblasts and fat cells two are native to the connective tissues. Other cells migrate through bloodstreams through these connective tissues.

Cells consist of cytoplasm, and a membrane encloses them. This cytoplasm contains different cell organelles like mitochondria, vacuoles, centrioles, chloroplast, ribosomes, endoplasmic reticulum, and many more things. People often wonder what suicidal bags are. To answer the question of what is the suicidal bag, we can say that lysosome is called the suicidal bag.

The lysosomes are usually found in animal cells but rare in plant cells. Ribosomes are of two types: the 70s found in prokaryotes and the 80s found in eukaryotes. Ribosomes are the structure that is important for protein synthesis. Robert Hooke first discovered the cell. Most plant and animal cells are visible only in a light microscope, and their size also varies from 1 to 100 micrometres. 


What Are Suicidal Bags Of Cells?

To answer what are suicidal bags of cell we can say that a suicide bag is called an exit bag or hood. This is used to exit some functions. Lysosomes are called suicidal bags of cells that contain different enzymes called lysosomes useful for digestion purposes. Found in cells and organelles, which are involved mainly in digestion purposes.

Material that is present outside is taken up by endocytosis, and material that is present outside is digested through autophagy. Their size varies greatly, and the larger one is ten times more than in size compared to the smaller one.

Belgian biologist Christian de Duve discovered an organelle and made clear the question that in every scientist's mind, what are suicidal bags. Lysosome sizes are from 0.1 micrometres to 1.2 micrometres. The range of pH is approx 4.5 - 5.0. The interior content is slightly acidic compared to the cytosol, which is a little bit basic.

Lysosomes are spherical or sometimes irregular in shape and membrane-bound structures. These are generated from the Golgi apparatus. They function as a recycling system of the cell because they contain hydrolytic enzymes.

These contain more than 60 different enzymes and more than 50 different membrane proteins in the cell. Enzymes of these lysosomes are synthesized in the rough endoplasmic reticulum. Then these enzymes are transferred to lysosomes from the Golgi apparatus by forming a small vesicle-like structure. Enzymes with mannose-6- phosphate tagging are specially for lysosomes.


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Functions Of The Suicidal Bag

Before going into the function part, first, we have to understand what a suicidal bag is. Well, lysosomes are regarded as the primary organ for this function. They contain a variety of enzymes that are mainly for the digestion purpose of biomolecules. It involves nucleic acid, lipids, carbohydrates engulfment for digestion purposes. But to perform, these enzymes require an acidic environment. In addition to that, they are also helpful in the phagocytosis process. They integrate with different structures like phagosomes for the digestion of large structures for cellular digestion. Also helps in the digestion of foreign material, bacteria, and viruses. They are helpful in autophagy. They even can break down different materials with the help of this.


What Are Suicidal Bags Of Cells Found In The Body?

To answer the question of what are suicidal bags of cells, we can say that lysosomes are the main organelle. It is mainly of 4 types.

  • Primary lysosomes: They are newly formed lysosomes from the Golgi complex. They are very small in size and contain hydrolytic enzymes in the form of small vacuoles. They are not fully functional to become the functional need to fuse it with endosomes.

  • Secondary lysosomes: these are hetero phagosomes or also called digestive vacuoles. Formation of this takes place after the fusion of lysosomes with phagosomes. Then this complex helps in the digestion process.

  • Residual lysosomes or tertiary lysosomes: These types of lysosomes contain residual wastes. Normally they fuse with the plasma membrane to throw all remains and debris out of the cell. This process of throwing out debris outside the cell is called exocytosis. Sometimes due to failure of this function, residues remain inside the body, and this causes different malfunctions. This leads to different diseases like hepatitis, poly-nephritis, hurler's disease, and many more different disorders.

  • Autophagic lysosomes: formation of these lysosomes occurs when primary lysosomes cover the worn-out cells in the body. It helps in the disposal of cell debris. Besides all these removals of cell debris, worn cells, tissues, these are also helpful in removing an internal obstruction from the body.

 

So, we can conclude that its main function is intracellular digestion, extracellular digestion, autophagy, mobilization of reserves, removal of obstructions, and help in defence purposes.

The main problem or disease in this is genetically inherent deficiencies called LSD (lysosomal storage deficiency). This is an inborn error in metabolism and mainly causes due to dysfunction of lysosome enzymes. These are very rare cases, and many are due to deficiency of an enzyme, acid hydrolase. Other dysfunctions of lysosomes are also causing this.

FAQs on Suicidal Bags of Cell

Question 1: What are suicidal bags and the role of the suicidal bag in saliva?

Answer: Lysozyme is an enzyme that is found in lysosomes. Helps in the breaking of protein. Lysozyme plays a very important role in saliva. Saliva is mainly to protect our oral cavity and oral tissues. It is one of the important functions of saliva. Saliva can inhibit a large number of carcinogen acid-producing bacteria. Saliva contains antibacterial proteins like immunoglobulin (IgG, IgM). Also contains some non-immunoglobulins like lysozyme, lectin protein, saliva peroxidase, and many different enzymes. These all are very important for the normal function of saliva. These contents in saliva provide you with an idea about local and systemic diseases like oral cancers, breast cancers, and many diseases. Lysozyme is an important antibacterial component that works as a host non-immune defence system.

Question 2: Are lysozyme and lysosome two different things?

Answer: Yes, lysozyme and lysosomes are two different things. The lysosome is an organelle of a cell that is a suicidal bag; meanwhile, lysozyme is a proteolytic enzyme. Lysosomes are a single membrane structure, and lysozyme is a hydrolytic enzyme. Lysosomes are called suicidal bags of the cell because they can destroy cells. And this destroying capability is because of the lysozyme enzyme that is present in the lysosome. With the help of this enzyme, lysosomes can destroy old cells from the body. This function is very important to replace old cells with new cells. Lysosomes can digest cell organelles, food particles, and viruses, while lysozyme can break the bonds between the cell walls of bacteria. The bacterial cell wall contains N-acetylglucosamine and N-acetyl muramic acid. They act on a specific site only.

Question 3: What are suicidal bags of cells and their role in phagocytosis?

Answer: Lysosome is a cell organelle that contains lysozyme. And lysozyme is a hydrolytic enzyme that helps in digestion purposes. They can destroy the foreign particles inside our bodies. They play a very important role in the phagocytosis process. When a foreign particle enters into the body, at that time, macrophages engulf that foreign body; this is also called phagocytosis. Then they store this on a phagosome. Then this phagosome binds with lysosomes to form a complex structure called phagolysosomes. These are oxygen-independent microorganisms. Because of this, they can perform their work effectively in the body. They help and defend our body from microorganisms by the phagocytosis process with the help of macrophages.

Question 4: In which cell lysosomes are present in high amounts?

Answer:  Lysosomes are found in all animal cells. But due to its different functions, this is mainly the highest amount in disease-fighting cells. These disease-fighting cells are white blood cells that are why they are found in the highest amount in it. So, they have to digest more cells compared to any other cells. They have to digest foreign materials, viruses, and different bacteria from the body. That is why they need this in the highest amount. Several diseases are caused due to disorders in lysosome function. They are found in saliva, tears, and they play a very important role in preventing disease.