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Difference between Methanol and Ethanol

Last updated date: 16th Apr 2024
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What is Methanol and Ethanol: Introduction

Methanol and ethanol are two types of alcohol compounds that play essential roles in various applications. These alcohols have distinct characteristics and uses, each with its own example of real-life application. From powering race cars to fueling our drinks, alcohols like methanol and ethanol find diverse applications in our everyday lives. Methanol, also known as wood alcohol, and ethanol, commonly known as drinking alcohol, offer unique properties that make them useful in different contexts.

Understanding the difference between methanol and ethanol is essential due to their varying properties and potential risks associated with their use. In this article, we will explore the dissimilarities between methanol and ethanol, explaining their properties, differences in chemical structure, uses, and potential hazards.

Defining Methanol

Methanol: Methanol, also known as methyl alcohol or wood alcohol, is the simplest alcohol with the chemical formula CH3OH. It is a colorless liquid that is highly volatile and flammable. Methanol is commonly produced from the destructive distillation of wood, but it can also be synthesized from carbon monoxide and hydrogen. It is widely used as a solvent, antifreeze, and as a raw material in the production of formaldehyde, acetic acid, and other chemicals.

Defining Ethanol

Ethanol: Ethanol, also referred to as ethyl alcohol or grain alcohol, is a clear, colorless liquid with the chemical formula C2H5OH. It is produced through the fermentation of sugars by yeast or bacteria, a process commonly used in the production of alcoholic beverages. Ethanol is also synthesized through chemical reactions, such as the hydration of ethylene. It has a wide range of applications, including as a solvent, fuel additive, disinfectant, and as the primary ingredient in alcoholic beverages.

Characteristics of Methanol and Ethanol

Physical Properties: Methanol and ethanol have similar physical properties, such as being colorless liquids with a characteristic odor. Both compounds are miscible in water, meaning they can mix with water in any proportion. However, methanol has a lower boiling point (64.7°C) compared to ethanol (78.4°C), which makes it more volatile. 

Toxicity and Risks: One of the most crucial  methanol and ethanol difference lies in their toxicity. Methanol is highly toxic and can cause severe health effects, including blindness, organ failure, and even death, if ingested in significant quantities. Ethanol, when consumed in moderation, has a much lower toxicity and is metabolized by the body into less harmful byproducts.

Uses and Applications

Industrial Applications: Methanol is commonly used as a solvent in various industries, including paint, varnish, and chemical manufacturing. It is also utilised as a fuel in some specialised engines and as an antifreeze agent. Ethanol is extensively used in pharmaceuticals, cosmetics, and personal care products. It is also a vital ingredient in the production of alcoholic beverages and serves as a biofuel additive to gasoline. 

Medical Applications: Ethanol has antiseptic properties and is often used as a disinfectant for wounds and medical equipment. In contrast, methanol is not suitable for medical applications due to its high toxicity.

Fuel and Energy: Ethanol is widely used as a biofuel additive to gasoline, primarily to reduce emissions and promote cleaner combustion. Methanol is also used as an alternative fuel, particularly in racing cars and some fuel cell systems, although its use is less prevalent compared to ethanol.

Differences between Methanol and Ethanol

S. No.





Chemical Formula





Destructive distillation of wood, synthesis from carbon monoxide and hydrogen

Colorless liquid

Fermentation of sugars by yeast or bacteria, chemical reactions such as hydration of ethylene

Colorless liquid


Boiling point




Physical State

Colorless liquid

Colorless liquid



More Volatile

Less Volatile



Miscible in water

Miscible in water



Highly toxic, can cause blindness, organ failure, and death if ingested

Lower-toxicity metabolized by the body into less harmful byproducts


Industrial Uses

Solvent, antifreeze, raw material for chemicals manufacturing

Solvent, disinfectant, an ingredient in pharmaceuticals and cosmetics


Fuel Applications

Used as a fuel in specialized engines, alternative fuel in some systems

Biofuel additive to gasoline, reduces emissions, promotes cleaner combustion


Potential Hazards

Methanol: Methanol poses significant health hazards due to its toxicity. Ingesting or inhaling methanol can cause severe poisoning symptoms, including dizziness, nausea, vomiting, abdominal pain, blindness, and even death. It is important to handle methanol with extreme caution and ensure proper ventilation in areas where it is used. 

Ethanol: While moderate consumption of ethanol in the form of alcoholic beverages is generally safe for most adults, excessive consumption can lead to alcohol poisoning, impaired judgment, liver damage, and addiction. Ethanol should be used responsibly and in accordance with legal regulations regarding alcohol consumption.


In summary, methanol and ethanol are two alcohol compounds that differ significantly in terms of their chemical composition, properties, uses, and potential risks. Methanol is highly toxic and primarily used in industrial applications as a solvent and antifreeze, while ethanol, with lower toxicity, finds use in various industries, including pharmaceuticals, cosmetics, and as a fuel additive. Understanding the distinctions between methanol and ethanol is essential for their safe and appropriate usage in different contexts.

FAQs on Difference between Methanol and Ethanol

1. Why is methanol considered more toxic than ethanol?

Methanol is considered more toxic than ethanol due to differences in how they are metabolised by the body. Methanol is metabolised into formaldehyde and formic acid, which are highly toxic substances. In contrast, ethanol is metabolised into acetaldehyde and then further broken down into less harmful byproducts.

2. What are the primary uses of methanol and ethanol as alternative fuels?

Methanol is commonly used as fuel in specialised engines, such as racing cars and fuel cells. It is also used as an additive in gasoline for improved combustion and reduced emissions. Ethanol, on the other hand, is widely used as a biofuel additive to gasoline and is used in flexible-fuel vehicles. It promotes cleaner combustion and helps reduce greenhouse gas emissions.

3. How can methanol and ethanol be differentiated using a simple chemical test?

One simple chemical test to differentiate between methanol and ethanol is the Lucas test. In this test, an equal volume of Lucas reagent (a mixture of concentrated hydrochloric acid and zinc chloride) is added to a sample containing either methanol or ethanol. Methanol does not react with the Lucas reagent and remains clear, while ethanol reacts rapidly to form a cloudy precipitate of ethyl chloride.