

Understand the Key Phases of Cell Division - Anaphase 1 and Anaphase 2
Anaphase 1 is the stage in meiosis I where homologous chromosomes separate and move to opposite poles, reducing the chromosome number from diploid to haploid. Anaphase 2 is the stage in meiosis II where sister chromatids separate at their centromeres and move to opposite poles.
Understanding the difference between anaphase 1 and anaphase 2 is essential for understanding how genetic diversity is created and how gametes form during reproduction.
Key Differences Between Anaphase 1 and Anaphase 2
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FAQs on Difference Between Anaphase 1 and Anaphase 2
1. What happens during anaphase 1?
During anaphase 1, homologous chromosome pairs separate and move to opposite poles of the cell. This reduces the chromosome number by half, creating haploid cells. Each chromosome still consists of two sister chromatids joined at the centromere.
2. What happens during anaphase 2?
In anaphase 2, sister chromatids separate at the centromere and move toward opposite poles. This process resembles mitotic anaphase but occurs in cells that are already haploid, resulting in four haploid daughter cells by the end of meiosis.
3. Why is anaphase 1 important for genetic diversity?
Anaphase 1 follows prophase 1 where crossing over occurs between homologous chromosomes. When these recombined chromosomes separate during anaphase 1, unique genetic combinations move to different daughter cells, increasing genetic diversity.
4. What would happen if anaphase 1 failed to occur properly?
If anaphase 1 fails, homologous chromosomes might not separate correctly, leading to aneuploidy (abnormal chromosome numbers) in gametes. This can cause genetic disorders in offspring, such as Down syndrome, when fertilization occurs.
5. How does anaphase in mitosis differ from anaphase 2?
Anaphase in mitosis and anaphase 2 both involve the separation of sister chromatids. However, mitotic anaphase occurs in diploid cells, maintaining the chromosome number, while anaphase 2 occurs in haploid cells produced after meiosis I.
6. What are the 4 stages of mitosis?
The four stages of mitosis are:
Prophase – Chromosomes condense.
Metaphase – Chromosomes align at the centre.
Anaphase – Sister chromatids separate.
Telophase – Two new nuclei form.
7. What is a homologous pair?
A homologous pair consists of two chromosomes (one from each parent) that have the same genes but may have different versions (alleles). They separate during anaphase 1.
8. How many chromosomes and chromatids are in anaphase 1?
In anaphase 1, there are 46 chromosomes (23 pairs) in humans, each made of two chromatids, but only 23 chromosomes move to each pole.
9. What are the differences between metaphase 1 and metaphase 2?
Metaphase 1 happens in meiosis 1, where homologous chromosome pairs line up in the centre of the cell. These pairs are separated later.
Metaphase 2 happens in meiosis 2, where individual chromosomes (not pairs) line up in the centre. Here, sister chromatids are separated.
Metaphase 1 deals with chromosome pairs, while metaphase 2 deals with single chromosomes.
10. What is the significance of anaphase 1?
Anaphase 1 is an important step in meiosis, the process that creates sperm and egg cells. In this stage, paired chromosomes (homologous chromosomes) are pulled apart to opposite sides of the cell. This helps in reducing the chromosome number by half, making sure each new cell gets the right amount of genetic material. It also increases genetic diversity by shuffling genetic traits. This step is crucial for healthy reproduction.
11. What is the significance of anaphase 2?
Anaphase 2 is an important step in meiosis, where the sister chromatids of each chromosome are pulled apart to opposite ends of the cell. This ensures that each new cell gets the right number of chromosomes. It helps in genetic diversity and is crucial for forming healthy eggs and sperm. Without this step, cells may end up with too many or too few chromosomes, leading to genetic disorders.





