Question

The enzyme responsible for transposition is:
A) Transposase
B) Recombinase
C) Ligase
D) Endonuclease

Answer 1

Hint:In genetics, the term transposition refers to the removal and the transfer of a segment of DNA starting with one site then onto the next of the same or different chromosome. Transposable elements are also called as jumping genes which change their position on the DNA.

Complete answer:
Transposition is not the same as the transfer of genes from parents to the offspring through reproduction, for example, sexual and asexual reproduction (vertical gene transfer). In transposition, the genes are transfer starting with one organism then onto the next through duplicating and inserting measure. Transposition represents the antibiotic resistance and transmission of virulence in specific microbes. The mobile segment of DNA that is related with transposition is called transposon or jumping genes.
Transposase is a enzyme associated with the transposition. Transposition relates to the level exchange of hereditary material between living beings. The enzyme binds to the transposon, i.e. a DNA sequence which are capable for replicating and embedding copies inside the genomes. The transposons bear gene coding for transposases. Transposases can catalyze the copying and inserting of a part of a genome or through a replicative transposition mechanism. The term transposes is the first used in a report about cloning a enzyme required for the transposition of the Tn3 transposon. Example of transposases are the transposase Tn5 and the Is10 transposase. Transposase Tn5 is a ribonuclease coded by a transposon that incorporates the code for antibiotic resistance, for example, kanamycin. The Is10 transposase is an enzyme that imparts region of sequence identify to other insertion element transposases of the Is4 family.

Hence the correct answer is option ‘A’.

Note:DNA transposons are helpful to analyse the regulatory genome, study embryonic development, identify genes and pathways involved in diseases or pathogenesis, and even contribute to quality treatment.