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Which of the following is necessary to start clotting of blood?
A. Heparin
B. Serotonin
C. Thromboplastin and Ca2
D. Fibrinogen and prothrombin

Last updated date: 16th Jul 2024
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Hint: Coagulation, otherwise called clotting, is the cycle by which blood changes from a fluid to a gel, framing blood coagulation. It is because of coagulation that a clot is formed when there is a flow of blood when we get injured. They produce proteins that help to coagulate.

Step by step answer:Coagulating is the cycle wherein blood changes from a fluid consistency to a gel framing blood coagulation. Thromboplastin and Ca++are important to begin the coagulation of blood. In the presence of Ca++, prothromboplastin is changed over into thromboplastin.
This thromboplastin and Ca++ changes over prothrombin into thrombin. The thrombin at that point changes over fibrinogen into fibrin. This fibrin at that point helps in blood thickening.
Heparin is utilized to forestall blood clusters from framing in individuals who have certain ailments or who are going through certain clinical methods that expand the possibility that coagulations will shape.
Serotonin or 5-hydroxytryptamine is a monoamine synapse. Its natural capacity is perplexing and multifaceted, regulating temperament, cognizance, reward, learning, memory, and various physiological cycles, for example, retching and vasoconstriction.
Fibrinogen (factor I) is a glycoprotein mind-boggling, made in the liver, that courses in the blood. Blood thickening is estimated utilizing standard tests for prothrombin.

Hence, option C is correct

Note: Coagulation is a clot that is formed when there is a flow of blood from the injured part. Here, thromboplastin and Ca++ changes over prothrombin into thrombin. Thrombin activates the fibrinogen and generates fibrin.