Question

Which of the following hormones secretes a gastric secretion?
A) Enterogastrone
B) Gastrin
C) CCK-PZ
D) Villikinin

Answer 1

Hint: Hormones that stimulate the secretion of gastric acids are peptide hormones which are released by G cells and affect heart or stomach.

Complete Answer:
1) Enterogastrone is a hormone which is secreted by mucosa from the gastrointestinal tract for the response to lipids which inhibits the motion of chyme. It acts same as GIp or gastric inhibitory peptide do and is affected in stomach motility.

2) Gastrin is a peptide hormone which stimulates the gastric acid secretion of the stomach and helps in gastric motility. It originated from G cells in the pyloric antrum of stomach and pancreas. It binds to cholecystokinin B receptors for the release of histamine. As it is a peptide hormone, its release is suppressed by peptide bonds in the lumen of the stomach.

3) Cholecystokinin is also known as CCK-PZ. It is also a peptide hormone that affects the gastrointestinal system that is responsible for stimulating digestion of protein and fat. Cholecystokinin is also further called pancreozymin that is synthesized by enteroendocrine cells, the first segment in the small intestine. It also acts as digestive.

4) Villikinin is a peptide hormone which is hypothetical in nature. It is secreted from the small intestine by the mucosa. It is a hormone that is believed to stay in explaining the activity of the extracts of intestine or intestinal villi.

Hence, Option B: Gastrin is the correct answer.

Note: A disease called the Zollinger–Ellison syndrome, gastrin is produced at excessive levels, often by a gastrinoma (gastrin-producing tumor, mostly benign) of the duodenum or the pancreas.