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Which of the following cellular metabolic processes can occur both in the presence or absence of ${ O }_{2}$?
(a) Glycolysis
(b) Fermentation
(c) TCA cycle
(d) Electron transport coupled with chemiosmosis.

Last updated date: 25th Jun 2024
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Hint: Respiration in an organism takes place aerobically or anaerobically. Both aerobic and anaerobic respiration starts with the breakdown of sugar which does not require oxygen. Later aerobic organisms undergo a further process of respiration in presence of oxygen which is not shown by an anaerobic organism.

Complete answer:
Glycolysis is a cellular metabolic process occurring in both aerobic and anaerobic organisms with the conversion of carbohydrates into pyruvic acid.
Glycolysis is also called an EMP pathway because it was discovered by Gustav Embden, Otto Meyerhof, and J.Parnas. This process occurs inside the cytoplasm with the release of ATP. Glycolysis starts with phosphorylation where glucose gets converted into glucose-6-phosphate by enzyme hexokinase and magnesium ion, the second step involves the isomerization of glucose-6-phosphate to fructose-6-phosphate by enzyme phosphohexose isomerase, the third step involves phosphorylation of fructose-6-phosphate to fructose 1,6 phosphate by enzyme phosphofructokinase and ATP, the fourth step involve splitting of Fructose 1,6 phosphate into two molecules of triose phosphate by enzyme aldolase, and dihydroxyacetone phosphate further converted into glyceraldehyde-3-phosphate with enzyme phosphotriose isomerase, the fifth step involve dehydrogenation of glyceraldehyde-3-phosphate to 1,3 diphosphoglycerate in presence of enzyme triose phosphate dehydrogenase, sixth step involves the conversion of 1,3- diphosphoglycerate to 3- phosphoglycerate by enzyme phosphoglycerate kinase, the seventh step of isomerization involve conversion of 3-phosphoglycerate into 2-phosphoglycerate, eight-step involve dehydration 2-phosphoglycerate to phosphoenolpyruvate by enzyme enolase and last step involve transfer of phosphoenolpyruvate to ADP with enzyme pyruvate kinase. This produces ATP with the formation of pyruvic acid.
So, the correct answer is ‘Glycolysis’.

Note: Phosphorylation at the third step of glycolysis activates the sugar and prevents it from getting out of the cell. The net gain of ATP takes place during glycolysis is 8 ATP, 2 direct from ADP, and 6 from the oxidation of NADH.
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