The bioactive molecule Cyclosporine A is used in:
A. Whooping cough
B. Diphtheria
C. Leprosy
D. Organ-transplant patients
Answer
393.3k+ views
Hint: Cyclosporine (cyclosporin A) is a cyclic polypeptide immunosuppressant. It is a product of fungal metabolism and is made up of 11 amino acids. Cyclosporine is used alone or in conjunction with other immunosuppressants to treat or prevent organ rejection like liver, kidney, and heart transplants.
Complete Step-by-step answer:
Cyclosporin A is a drug acquired from soil fungi Trichoderma polysporum. It is used to prevent transplant rejection in the case of tissue and organ as it functions as a powerful immunosuppressant. It is also used in the case of nephrotic syndrome and rheumatoid arthritis.
Whooping cough is an infectious respiratory tract infection. In many individuals, it's marked by a serious hacking cough followed by a high-pitched intake of breath that sounds like "whoop." Prior to the vaccine was first developed, whooping cough was considered an infantile disease. Currently, whooping cough affects mainly children too young to have completed the entire course of vaccinations and teenagers and adults whose immunity was lost.
Diphtheria is a severe infection caused by strains of bacterium known as Corynebacterium diphtheriae that make a toxin (poison). It is the toxin that can cause humans to get too sick. Diphtheria bacteria be transmitted from one person to another, usually through respiratory droplets, like from sneezing or coughing.
Hansen's disease (also called leprosy) is an infection caused by a slow-growing bacterium known as Mycobacterium leprae. This can affect skin, nerves, eyes, and the lining of the nose (nasal mucosa). With early detection and treatment, the disease is treatable.
Therefore the correct answer is Option D.
Note: In 1978-79 the world's first successful outcomes of the utilisation of cyclosporine in kidneys were stated. Cyclosporine was the first single drug that can control rejection. In 1982-83 initial trials showed the advantage of treatment with cyclosporine in kidney recipients in comparison with steroids and azathioprine. In the 1980s solid-organ transplantation entered the cyclosporine era with unexpected-for results in a heart transplant.
Complete Step-by-step answer:
Cyclosporin A is a drug acquired from soil fungi Trichoderma polysporum. It is used to prevent transplant rejection in the case of tissue and organ as it functions as a powerful immunosuppressant. It is also used in the case of nephrotic syndrome and rheumatoid arthritis.
Whooping cough is an infectious respiratory tract infection. In many individuals, it's marked by a serious hacking cough followed by a high-pitched intake of breath that sounds like "whoop." Prior to the vaccine was first developed, whooping cough was considered an infantile disease. Currently, whooping cough affects mainly children too young to have completed the entire course of vaccinations and teenagers and adults whose immunity was lost.
Diphtheria is a severe infection caused by strains of bacterium known as Corynebacterium diphtheriae that make a toxin (poison). It is the toxin that can cause humans to get too sick. Diphtheria bacteria be transmitted from one person to another, usually through respiratory droplets, like from sneezing or coughing.
Hansen's disease (also called leprosy) is an infection caused by a slow-growing bacterium known as Mycobacterium leprae. This can affect skin, nerves, eyes, and the lining of the nose (nasal mucosa). With early detection and treatment, the disease is treatable.
Therefore the correct answer is Option D.
Note: In 1978-79 the world's first successful outcomes of the utilisation of cyclosporine in kidneys were stated. Cyclosporine was the first single drug that can control rejection. In 1982-83 initial trials showed the advantage of treatment with cyclosporine in kidney recipients in comparison with steroids and azathioprine. In the 1980s solid-organ transplantation entered the cyclosporine era with unexpected-for results in a heart transplant.
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