Question

Secretion of gastric juice is stopped by
(a) Gastrin
(b) Secretin
(c) Enterogastrone
(d) Cholecystokinin

Answer 1

Hint: It is secreted from the duodenum in the lower gastrointestinal tract and causes contraction of the gallbladder. Its function is almost the same as Gastric Inhibitory Peptide (GIP).

Complete answer:
Enterogastrone is secreted from the mucosa of duodenal. It is secreted in response to fatty food in the stomach or small intestine. It is also secreted when sugars and proteins are in the intestine and decreases the secretion of gastric juices. Glands and muscles of the stomach have the enterogastrone which is transported by the bloodstream. The gastric movements and secretions are inhibited by enterogastrone by blocking the production or activity of gastrin. Ironically gastrin is the hormone that initially causes these functions. The amount of acid produced is reduced thus enterogastrone may slow down stomach emptying. High acid content is needed for digestion and also causes the valve between the stomach and intestine to relax by allowing food to pass. Two hormones secretin and cholecystokinin are known now which were taught to be enterogastrone in the intestine. Many functions that were thought to be performed by enterogastrone are now reassigned to other hormones.
So, the correct answer is 'Enterogastrone'.

Note:
In the stomach, the parietal cells secrete gastrin this stimulates the secretion of the gastric juices from the gastric glands. Secretin is secreted in the duodenum and regulates water homeostasis. It regulates the secretion of the stomach, pancreas, and liver and inhibits the secretion of gastric juices. Cholecystokinin is also secreted in the duodenum by the enteroendocrine and stimulating the digestion of fat and protein.