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Last updated date: 06th Dec 2023
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MVSAT Dec 2023

One picogram (pg) is equal to how many base pairs (bp)?
(A) $1 \times {10^9}$
(B) $0.965 \times {10^9}$
(C) $0.965 \times {10^{10}}$
(D) $0.963 \times {10^8}$

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Hint: Microbes have genomes, which are mostly smaller than those of macroscopic creatures like humans. Base pairs are used to calculate DNA. The human genome, for example, is 3.4 billion base pairs long, while Escherichia coli, a common intestinal bacteria, is 4.6 million base pairs long.

Complete answer:
Base pairs are often used to determine the size of a single gene within a DNA molecule. The number of nucleotides in one of the strands is proportional to the total number of base pairs (each nucleotide consists of a base pair, a deoxyribose sugar, and a phosphate group).

The chemical formula can be used to measure the weight of nucleotide bases, and relative weights can be used to compare the weight with the estimated number of bases in a given sample of DNA. Using this method, it was calculated that one nucleotide pair has a mean weight of $1.023 \times {10^9}pg$, and $1pg$ of DNA represents$978000000$ base pairs.

$(978000000) \times $ (number of nucleotide pairs) is the right formula for translating picograms of DNA to nucleotide pairs (DNA content in picograms).
A lower valuation has been stated by some employees $(965000000)$which is $0.965 \times {10^9}$.

Hence, the correct answer is option (B).

Note: Microbes are rarely measured individually, but they may be weighed in bulk for different tests. Estimating the number of microbes may be used to determine the weight of an actual microbe.