Question

In alcoholism, this enzyme is elevated
A. Acid phosphatase
B. Hepatitis
C. Serum glutamate pyruvate transaminase
D. Glutamyl transpeptidase

Answer 1

Hint:
Alcoholism can result in an increase in glutamyl transpeptidase enzyme activity (GTP). Elevated GTP levels have been associated with poor alcohol detoxification, relapse, and many cases of alcoholism.
This enzyme aids in the breakdown of proteins into their individual amino acids, which the body can then utilize. Due to difficulties with protein elimination, GT levels are typically higher in alcohol addicts than in healthy individuals. This enzyme thus has the potential to catalyze the creation of toxic metabolites that support alcohol dependence and toxicity.

Complete answer:
High levels of GGT in the blood could indicate liver illness or bile duct injury. Bile enters and exits the liver through tubes called bile ducts. The liver produces a fluid called bile. For digestion, it is essential.
Typically, high GGT levels indicate a liver condition. Among the signs of liver issues are skin and eyes turning yellow (jaundice) abdominal distension brought on by fluid retention. Additionally, more recent investigations have shown that individuals with severe fatty liver disease have elevated serum GGT levels.

Option ‘D’ is correct

Note:
This enzyme, also known as glutamyl transpeptidase, is increased in alcoholism. Increased synthesis of glutamate in the brain due to elevated levels of this enzyme may be the cause of some of the negative effects of alcohol consumption.
An enzyme called glutamyl transpeptidase is frequently increased in alcoholism. This enzyme aids in the breakdown of proteins, notably those linked to alcoholism and substance dependence.