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Assertion
In dialyzer, the plasma protein of the blood cannot be filtered but molecules like urea, uric acid, creatinine and ions can be filtered.
Reason
The cellophane membrane used in dialyzer is permeable to macromolecules but impermeable to micromolecules.
(a) Both assertion and reason are correct and reason is the correct explanation for the assertion.
(b) Both assertion and reason are correct but reason is not the correct explanation for assertion.
(c) Assertion is correct but reason is incorrect.
(d) Both assertion and reason are incorrect.

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Last updated date: 20th Jun 2024
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Answer
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Hint: The membrane transport characteristics of a dialyzer, is the ability of membrane binding mechanism by which some low- molecular weight (LMW) proteins are appreciably removed from the bloodstream.

Complete step by step answer:
Hemodialysis cellophane membranes are one of the first applications in dialysis biological fluid like blood to eliminate unwanted substances such as urea and creatinine. The cellophane membranes were used in planar form to dialyzed blood against electrolyte solution in artificial kidneys.
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So, the correct answer is, ‘Assertion is correct but reason is incorrect.’

Additional information:
- Dialyzers are hollow- fiber artificial kidneys devices that contain thousands of tiny tubules which act as semipermeable membranes.
- The blood flows through these tubules, while a solution or the dialysate circulates around the tubules.
- The exchange of wastes from the blood from the patient to the dialysate occurs through the semipermeable membrane of the tubules.
Procedure:
- Patient access is prepared and cannulated.
- Heparin is administered.
- Heparin and red blood flows through semi permeable dialysis in one direction and dialysis solution surrounds the membrane and flows in the opposite direction.
- Dialysis solution consists of highly purified water into which sodium, potassium, calcium, magnesium chloride, and dextrose is added, bicarbonate is added to achieve the proper pH.
- By the process of diffusion solute in the form of electrolytes, metabolic waste products acid base balance components can be removed or added to the blood.
- The excess water is removed from the blood by ultrafiltration.
- The pure blood is then returned to the body through patient access.

Note:
- Impure blood is removed from the body and filtered through a man made membrane called a dialyzer or artificial kidney and then the filtered blood is returned to the body.
- A dialyzer is composed of three or four components.
> Blood compartment
> DialysateI compartment
> Semi permeable membrane separating
> Membrane support structure