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Assertion: During the physiology of excretion, deamination does not take place in the liver.
Reason: Deamination is a process to make use of excess amino acids, which cannot be incorporated into protoplasm.
(a)Both assertion and reason are correct and the reason is the correct explanation for the assertion.
(b)Both assertion and reason are correct but the reason is not the correct explanation for the assertion.
(c)Assertion is correct but the reason is incorrect
(d)Both assertion and reason are incorrect

Last updated date: 20th Jun 2024
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Hint: Deamination is the removal of an amino group from a molecule catalyzed by enzymes known as deaminases. The amino group is then converted to ammonia which is very toxic for living organisms and thus has to be excreted out immediately.

Complete answer:
Deamination is the process of removal of an amine group from an organic compound present in the body. This process takes place in the liver but the deamination of glutamate is also seen in the kidneys. It occurs in the body when there are excess amino acids present or the body requires amino acids for fulfilling the energy demands of the body. The amine group is converted into ammonia during deamination but it is toxic to the body and hence it is further converted into urea by the addition of carbon dioxide which is non-toxic and thus can be safely excreted from the body.

Additional Information: -The process of deamination is used to synthesize non-essential amino acids in the body.
-The remaining carbon compound from which the amine group was taken is used to produce energy or synthesize new organic compounds like glucose, acetyl CoA.
-Deamination occurs to carry out homeostasis (equilibrium) in the body which means if there is an excess of amino acids it will reduce them or if there is a shortage of any carbon compound, amino acids will be converted into them.
-The products of deamination like ammonia and urea are used to regulate the pH of the body fluids.
So, the correct option is ‘Both assertion and reason are incorrect’.

Note: -Essential amino acids are the amino acids that cannot be synthesized by the body and thus have to be taken through diet to avoid their deficiency. Examples-Leucine, lysine, valine, histidine, etc.
-Non-essential amino acids are the amino acids that can be synthesized by the body and thus even if they are not taken through diet, there won’t be a deficiency of them in the body.
-Examples of non-essential amino acids include alanine, arginine, serine, tyrosine, etc.