
Write the mechanism of Amination.

Answer
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Hint: The process by which an amine group is added to an organic molecule is known as amination. Enzymes that are used as catalysts in the amination reaction are known as aminase. There are different methods of amination like reductive amination, acid-catalyzed hydroamination, Mannich reaction, Ritter reaction, electrophilic amination, hydroamination, etc.
Complete step by step solution:
One of the methods of animation is electrophilic amination reaction. In electrophilic amination reaction, the formation of a C-N bond takes place by reaction between a nucleophilic carbanion and electrophilic nitrogen source.
There are various types of electrophiles that can be used like chloramines, hydrazines, hydroxylamines or oxaziridines. Some reactions may also use imines, azides, azo, or oxime compounds, among others. These electrophiles are mostly amines which are substituted with groups which are electron-withdrawing in nature.
The above amination reaction is a type of an electrophilic amination reaction. It involves benzene as the nucleophilic carbon ion and hydrazoic acid , an azide, as the electrophilic nitrogen source.
Direct electrophilic amination is one of the most promising methods for production of aromatic amines as it is rapid as well as cost-effective. It is also a one-step reaction route for the production of aromatic amines.
This is the proposed single step reaction mechanism for direction amination of benzene.
Note: It must be noted that the electrophilic nitrogen source used is an azide, hydrazoic acid , and not ammonia . Ammonia is used for amination of alcohols in the presence of solid acid catalysts to produce alkyl amines at an industrial level through acid-catalyzed hydroamination method.
Complete step by step solution:
One of the methods of animation is electrophilic amination reaction. In electrophilic amination reaction, the formation of a C-N bond takes place by reaction between a nucleophilic carbanion and electrophilic nitrogen source.
There are various types of electrophiles that can be used like chloramines, hydrazines, hydroxylamines or oxaziridines. Some reactions may also use imines, azides, azo, or oxime compounds, among others. These electrophiles are mostly amines which are substituted with groups which are electron-withdrawing in nature.
The above amination reaction is a type of an electrophilic amination reaction. It involves benzene
Direct electrophilic amination is one of the most promising methods for production of aromatic amines as it is rapid as well as cost-effective. It is also a one-step reaction route for the production of aromatic amines.

This is the proposed single step reaction mechanism for direction amination of benzene.
Note: It must be noted that the electrophilic nitrogen source used is an azide, hydrazoic acid
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