Question

Thyrotropin-releasing hormone (TRH) is secreted by
(a)Hypothalamus
(b)Adenohypophysis
(c)Pars intermedia
(d)Neurohypophysis

Answer 1

Hint: They are a small region of the brain. Located at the bottom of the brain, near the pituitary. They’re considered to be a link structure between the nervous system and the endocrine system, its main function is to keep up the homeostasis of the body.

Complete answer:
Thyrotropin-releasing hormone (TRH) is secreted by the hypothalamus. It plays a crucial role in the regulation of thyroid activity. TRH is one among the tiniest hormones within the body, consisting of a miniature chain of just three amino acid building blocks. It’s made by a cluster of nerve cells within the hypothalamus, a region at the bottom of the brain just above the pituitary. The nerve fibers that begin it carry the TRH and release it into the blood to manage the formation and secretion of thyroid-stimulating hormone within the pituitary gland, which successively regulates the assembly of thyroid hormones within the thyroid gland. TRH is extremely short-lived, lasting for a matter of two minutes and traveling less than an inch within the bloodstream to the pituitary before it's broken down.

Additional Information: The secretion of TRH by the hypothalamus also can stimulate the discharge of another hormone from the pituitary gland, prolactin. Aside from its role on top of things of thyroid-stimulating hormone and prolactin release, TRH features a wider distribution in tissues of the nervous system where it's going to act as a neurotransmitter. As an example, an injection of TRH has effects on the arousal and feeding centers of the brain, causing wakefulness and loss of appetite.
So, the correct answer is ‘hypothalamus’.

Note: TRH is employed clinically by injection to check the response of the anterior pituitary gland; this procedure is understood as a TRH test. This is often done as a diagnostic test of thyroid disorders like secondary hypothyroidism and in acromegaly.
TRH has been shown in mice to be an anti-aging agent with a broad spectrum of activities that, due to their actions, suggest that TRH features a fundamental role within the regulation of metabolic and hormonal functions.