Question

This about alpha-thalassemia is correct
A. The number of gene mutations decides the severity of the condition
B. Haemoglobin fails to produce enough alpha protein in alpha-thalassemia
C. Alpha-thalassemia is common in Southeast Asia, Southern Asia, India, etc
D. All of these

Answer 1

Hint:
A blood condition called thalassemia, pronounced thal-uh-SEE-mee-uh is hereditary. This indicates that it is inherited through the genes of one or both parents. Your body creates less haemoglobin than usual when you have thalassemia. Red blood cells contain the iron-rich protein known as haemoglobin. All areas of the body receive oxygen thanks to it.
Alpha and beta thalassemia are the two primary subtypes. Each type affects a different gene.
Anaemia due to thalassemia can be minor or severe. When your body does not have enough haemoglobin or red blood cells, anaemia develops. Depending on how many genes are impacted, anaemia can vary in severity and kind.

Complete answer:
Silent carrier of alpha thalassemia: There are no signs of this type.
Carrier of alpha thalassemia: You might have slight anaemia. You could be symptom-free. Alternatively, you could be experiencing minor symptoms like mild weariness or intolerance to strenuous activity.
Haemoglobin H illness: These symptoms range from mild to severe. Fatigue and an intolerance to exercise are two of these. Leg ulcers, yellow skin, an enlarged liver or spleen, and other symptoms are also possible. You run a higher chance of passing on the most serious kind, major alpha thalassemia, to your offspring.
Major in alpha thalassemia: Typically, babies with this kind pass away before birth.

Option ‘D’ is correct

Note:
Africa, the Middle East, India, Southeast Asia, Southern China, and the Mediterranean region are the regions of the world where alpha thalassemia is most frequently seen.
The tests listed below may help determine whether you are a carrier and can carry the condition to your offspring:
Thorough blood count (CBC): This examination measures the size, quantity, and maturity of certain blood cells in a predetermined amount of blood.