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The study of cell nuclei, especially with reference to their chromosomes is known as:
A. Tychology
B. Chromosornology
C. Pycnology
D. Karyology

Answer
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Hint: The word karyon is referred to as the nucleus.
For example, prokaryotic means the previous nucleus or poor nucleus whereas eukaryotic means modern nucleus. Again, in the case of cell division, karyokinesis means the division of the nucleus.

Complete answer: A karyotype can be defined as the study of the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
1. The term is also used to describe the complete set of chromosomes present in a species or in an individual organism. It is also used for a test that detects this complement or measures the number.
2. Karyotypes define the chromosome count of an organism and how the chromosomes exactly look like under a microscope. The chromosomes are represented by rearranging a photomicrograph in a standard format which is known as a karyogram or ideogram.
3. It is present in pairs, well-ordered by size, and the position of centromere for the chromosomes of the same size.
4. The preparation and study of karyotypes is a part of cytogenetics.
5. The study of whole sets of nuclei by the reference of the chromosomes is known as karyology.

So, the correct answer is option D. karyology.

Note: The karyology study of the nucleus that is based on the chromosome is done by using the light and electron microscope, cytochemistry, and isotopic indicators such as autoradiography.