
The protein whose production gets affected in Duchenne muscular dystrophy is
A. Actin
B. Myotropin
C. Dystrophin
D. Leucovorin
Answer
356.7k+ views
Hint:
Muscular dystrophy comes in different forms, one of which being Duchenne. It quickly gets worse. The progression of other muscular dystrophies, such as Becker's muscular dystrophy, is substantially slower. A dystrophin gene deficiency is what causes Duchenne muscular dystrophy (a protein in the muscles). A genetic defect in the production of dystrophin, a protein that prevents muscle fibres from degrading when exposed to enzymes, results in Duchenne muscular dystrophy.
Cardiorespiratory failure continues to be the major cause of death in people with DMD in our demographic. A subgroup of males with DMD have cognitive dysfunction that does not worsen over time, including linguistic, short-term, and working memory difficulties.
Complete answer:
Dystrophin is a component of a protein complex in the skeletal and cardiac muscles that functions to fortify muscle fibres and guard against damage while muscles contract and rest. Researchers have discovered some of the mutated genes, which are brought on by a genetic mutation on one of the mother's X chromosomes. A genetic defect in the production of dystrophin, a protein that prevents muscle fibres from degrading when exposed to enzymes, results in Duchenne muscular dystrophy.
So, the protein whose production gets affected in Duchenne muscular dystrophy is Dystrophin.
Option ‘C’ is correct
Note:
When methotrexate (Rheumatrex, Trexall; a cancer chemotherapy drug) is used to treat some types of cancer, leucovorin is utilized to stop any negative effects. Leucovorin is also used to treat patients who unintentionally took an excessive amount of methotrexate or a comparable drug. Leucovorin is used as a countermeasure to the negative effects of the cancer drug methotrexate, which is administered in high doses. Additionally, it is used to prevent or cure some types of anemia
Muscular dystrophy comes in different forms, one of which being Duchenne. It quickly gets worse. The progression of other muscular dystrophies, such as Becker's muscular dystrophy, is substantially slower. A dystrophin gene deficiency is what causes Duchenne muscular dystrophy (a protein in the muscles). A genetic defect in the production of dystrophin, a protein that prevents muscle fibres from degrading when exposed to enzymes, results in Duchenne muscular dystrophy.
Cardiorespiratory failure continues to be the major cause of death in people with DMD in our demographic. A subgroup of males with DMD have cognitive dysfunction that does not worsen over time, including linguistic, short-term, and working memory difficulties.
Complete answer:
Dystrophin is a component of a protein complex in the skeletal and cardiac muscles that functions to fortify muscle fibres and guard against damage while muscles contract and rest. Researchers have discovered some of the mutated genes, which are brought on by a genetic mutation on one of the mother's X chromosomes. A genetic defect in the production of dystrophin, a protein that prevents muscle fibres from degrading when exposed to enzymes, results in Duchenne muscular dystrophy.
So, the protein whose production gets affected in Duchenne muscular dystrophy is Dystrophin.
Option ‘C’ is correct
Note:
When methotrexate (Rheumatrex, Trexall; a cancer chemotherapy drug) is used to treat some types of cancer, leucovorin is utilized to stop any negative effects. Leucovorin is also used to treat patients who unintentionally took an excessive amount of methotrexate or a comparable drug. Leucovorin is used as a countermeasure to the negative effects of the cancer drug methotrexate, which is administered in high doses. Additionally, it is used to prevent or cure some types of anemia
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