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The most common way of gene expression is regulated in both prokaryotes and eukaryotes is through the
A. Control of mRNA translation.
B. Breakdown of proteins formed by translation.
C. Prevention of DNA uncoiling prior to transcription
D. Control of gene transcription.

Answer
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Hint: The method through which a gene in a cell is activated to produce RNA and proteins. The RNA, the protein generated from the RNA, or the function of the protein in a cell can all be used to quantify gene expression.

Complete step by step solution:
A finely controlled process called gene expression enables a cell to react to its changing surroundings. It functions as an on/off switch to control when proteins are made as well as a volume control to increase or decrease the number of proteins produced. Gene expression is the process by which specific genes are activated to produce a required protein.
The process by which a cell reads the genetic information contained in the DNA to generate the molecule it requires is known as gene expression. In order to accomplish this, the cell decodes the genetic code and adds one of the 20 distinct amino acids, which serve as the building blocks for proteins, to each group of three letters.
The environment, comprising the external environment in which an organism is placed or develops as well as the organism's internal environment, which includes elements like its hormones and metabolism, can affect how genes are expressed in an organism. There are a number of strategies to control how genes are expressed, but transcriptional regulation is unquestionably the most widespread method.
So, option (A) is correct.

Note:
Gene expression is the result of transcription and translation working together. Transcription occurs in the cell nucleus and involves the transfer of information from a gene's DNA to a similar molecule called RNA (ribonucleic acid).