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The best cell division stage to observe the shape, size and number of chromosome is
A. Metaphase
B. Interphase
C. Prophase
D. Telophase

Answer
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Hint:Metaphase is a stage in the cell cycle where all the genetic material is condensing into the chromosomes. During this stage, the chromosomes appear in the cytoplasm of the cell and the nucleus disappears.

Complete step by step answer:One of the best cell division stages to observe the shape, size and the numbers of chromosomes is the metaphase. The chromosomes appear shortest and thickest during the metaphase and are arranged at the equator and form an apparent plate called as the equatorial or as the metaphase plate thus readily visible. Therefore, this phase is often chosen for karyotyping and for the chromosome analysis.
Therefore, the correct answer is option A.

Additional InformationThe phases involved in cell division are prophase, prometaphase metaphase, anaphase, and telophase. In prophase, separation of the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. In prometaphase, separation of the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. The physical barrier that encloses the nucleus, called a nuclear envelope, is broken down in this phase.
In metaphase, all the genetic material is condensing into the chromosomes.
These chromosomes then become more visible. During metaphase, the nucleus disappears and chromosomes begin to be visible in the cytoplasm of the cell. In anaphase, replicated chromosomes are split and the newly-copied chromosomes are moved to the opposite poles of the cell. In telophase, separation of the duplicated genetic material occurs in the nucleus of a parent cell into two identical daughter cells.

Note:There are two types of cell division: mitosis and meiosis.Meiosis is the type of cell division that creates egg and the sperm cells. Mitosis is the fundamental process for life.