Question

Mast cells secrete
(a) Histamine
(b) Haemoglobin
(c) Hippurin
(d) Myoglobin

Answer 1

Hint: It is an organic nitrogen containing compound which is involved in local immune responses. It is involved in the inflammatory response and has a central role as a mediator of itching.

Complete answer:
A mast cell is a migrant cell of animal tissue that contains many granules. Specifically, it's a kind of granulocyte derived from the myeloid somatic cell that's a part of the immune and neuroimmune systems.
During mast cell degradation histamine is secreted, which is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the central nervous system (CNS). Histamine is involved within the inflammatory response to foreign pathogens and features a central role as a mediator of itching.
So, the correct answer is ‘Histamine’.

Additional Information:
- Mast cells play a vital role in the inflammatory action.
- The mastocyte is extremely similar in both appearance and performance to the basophil.
- Their nuclei differ and the basophil nucleus is located while the mastocyte nucleus is round.
- The Mast cells in rodents are classically split into two subtypes: connective tissue- type mast cells and mucosal mast cells
- In allergies, mast cells remain inactive until an allergen binding to IgE is already coated upon the cell.

Note:
- A mast cell is also known as a mastocyte or a labrocyte. Intravenous injection of histamine causes a fall in blood pressure. As an integral part of the system, histamine could also be involved in system disorders.
- On the basis of unique staining characteristics and large granules, mast cells are first discovered by Paul Ehrlich.