Question

Erythropoietin is released by
A. Bone marrow
B. Spleen
C. Kidneys
D. Liver

Answer 1

Hint: Erythropoietin is an important hormone that's produced predominantly by specialised cells within the organ that acts as a filter. Once it's made, it acts on red blood cells to guard them against destruction. At an equivalent time, it stimulates stem cells of the bone marrow to extend the assembly of red blood cells.

Complete answer: Red blood cells are specialized cells that perform vital functions in the body, and erythropoietin is a hormone directly connected to these cells. Erythropoietin hormone is released by specially built interstitial fibroblasts within the kidney in close association with the peritubular capillary and proximal convoluted tubule. It is also produced in perisinusoidal cells within the liver. Erythropoietin stimulates other tissues within the body to supply and protect red blood cells. When the body isn't circulating enough oxygen within the blood, erythropoietin production increases. When oxygen levels are where they ought to be, it drops. This is often commonly seen when someone moves to a higher altitude where atmospheric pressure is lower and therefore the blood absorbs less oxygen. Increased erythropoietin production helps catch up on this.
So, the correct answer is option C.

Note: It is important to note that prime level erythropoietin receptor expression is localized to erythroid progenitor cells. While there are reports that EPO receptors are found during a number of other tissues, like heart, muscle, kidney and peripheral/central nerve tissue, those results are confounded by no specificity of reagents like anti-EpoR antibodies.