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What is the end product of glycogenolysis?

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Last updated date: 13th Jun 2024
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Answer
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Hint: The polymeric form of glucose molecules is known as glycogen. Insulin will convert the glucose that is present in excess in the blood into glycogen. Glycogenolysis is a process that occurs in the liver to produce glucose.
Glycogenolysis is the process of turning glycogen to glucose. The process of creating glycogen from glucose is known as gluconeogenesis. The term lysis refers to the process of fragmentation. Glycogenolysis is the process of breaking down glycogen into glucose.

Complete answer:
The term "glycogenolysis" refers to the process of breaking down a glycogen polymer into individual glucose units. Glycogen is primarily stored in the muscles and liver.
Glycogen is converted into glucose-$1$-phosphate and then glucose-$6$-phosphate during glycogenolysis.
Glycogen is a polymer made up of glucose as the primary monomer.
Glucose molecules are first hydrolyzed from the chain in glycogenolysis, releasing glucose-$1$-phosphate as a result. The phosphate group is later transferred to the C-$6$ position and glucose $6$-phosphate is formed.
The liver and kidney will then convert glucose $6$-phosphate into glucose.
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Hence, glucose is the end product of glycogenolysis.

Additional information:
This procedure is used to release glycogen from the liver and muscles into the bloodstream in the form of usable glucose units. The glycogenolysis pathway is followed as a result of neuronal signalling or hormone production. It usually occurs when the body is stressed due to a low blood sugar level or an emergency situation. When a person is confronted with a potentially dangerous circumstance, the body produces adrenaline or epinephrine. The fight or flight response is the term for this.

Note:
Glycogen is stored in the liver, accounting for around \[5\% \] of its weight. Glycogen is accumulated in the muscles at a rate of \[1 - 2\] percent of their total weight.
In most cases, glycogenolysis takes place in the liver. The liver does not immediately utilise the glucose produced by glycogen. Glucose, on the other hand, enters the bloodstream and is utilised by other cells in the body.