
Deficiency of VIII factor leads to
A. Haemophilia A
B. Haemophilia B
C. Haemophilia C
D. Haemophilia D.
Answer
576.9k+ views
Hint:In factor to VIII deficiency the body does not make enough factor VIII (factor 8), one of the substances the body needs to form a clot. The normal ranges for factor VIII ranges are 50% to 150%.
Complete answer:
To answer this question, first, we need to know about the factor VIII. Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a recessive X attached coagulation disorder. Factor VIII occurs in liver endothelial cells and sinusoidal cells outer of the liver all over the body.
Now, let us find the solution from the option.
>Hemophilia A is the usual kind of hemophilia and it occurs due to the shortage in factor VIII.
>Hemophilia B that is additionally known as Christmas disease, occurs because of lack of factor IX.
>Hemophilia C is a mild form of the disease which occurs by shortage of factor XI.
Thus, the correct option is A .i.e. Haemophilia A.
Note:Hemophilia A is the most usual intense bleeding disorder. Von Willebrand disease is the most common among all other bleeding disorders. Blood doesn't clot in the proper way in hemophilia A. This causes a person at danger of uncontrolled blood loss. In normal conditions, some proteins, like factor VIII, come together to produce blood clots and instantly prevent blood loss.
Complete answer:
To answer this question, first, we need to know about the factor VIII. Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene result in hemophilia A, a recessive X attached coagulation disorder. Factor VIII occurs in liver endothelial cells and sinusoidal cells outer of the liver all over the body.
Now, let us find the solution from the option.
>Hemophilia A is the usual kind of hemophilia and it occurs due to the shortage in factor VIII.
>Hemophilia B that is additionally known as Christmas disease, occurs because of lack of factor IX.
>Hemophilia C is a mild form of the disease which occurs by shortage of factor XI.
Thus, the correct option is A .i.e. Haemophilia A.
Note:Hemophilia A is the most usual intense bleeding disorder. Von Willebrand disease is the most common among all other bleeding disorders. Blood doesn't clot in the proper way in hemophilia A. This causes a person at danger of uncontrolled blood loss. In normal conditions, some proteins, like factor VIII, come together to produce blood clots and instantly prevent blood loss.
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