Question

Who carried out of the first electron microscopic studies on the Golgi apparatus?
A. Camillo
B. Cajal
C. Dalton and Felix
D. All of the above

Answer 1

Hint: Golgi apparatus is a complex organelle made of a stack of cisternae, a network of tubules, vesicles, and vacuoles.

Complete answer: After synthesis and translocation into the endoplasmic reticulum, proteins are exported to the Golgi apparatus, a multi-compartment organelle that is the protein modifying, packaging, and distribution center of the secretory pathway.

John Dalton was an English chemist, physicist, and meteorologist. He is popularly known for introducing the atomic theory into chemistry, and for his research into color blindness, sometimes referred to as Daltonism in his honour.
1. The biogenesis of the Golgi through localization of resident proteins and its inheritance during cell division is also described.
2. Emphasis is placed on processes, such as protein transport through the Golgi, that are incompletely understood and remain focal points for current research in this field.
3. The transport of proteins and lipids from their site of synthesis at the endoplasmic reticulum (ER) to the cell surface is mediated by the secretory pathway and is an essential process in eukaryotic organisms.
4. Depending on the cell type, an individual cell section may contain many Golgi stacks that appear to be separate structures, but this often represents a single Golgi ribbon winding in and out of the section plane.

So the correct answer is A.

Note: The pendulum has swung back to cisternal maturation as the most popular model to describe anterograde transport of secretory proteins through this organelle. However, many questions remain concerning the mechanism of cisternal maturation.
For example, what is the precise role of COPI-coated vesicles in the maturation process.