Question

What are the \[12\] blood clotting factors?

Answer 1

Hint: When a blood vessel is damaged, blood clotting, or coagulation, is a crucial mechanism that avoids excessive bleeding. Platelets (a kind of blood cell) and; proteins in plasma (blood's liquid component) work together to stop bleeding; by creating a clot over the wound. Clotting factors are proteinaceous biomolecules which along with Vitamin K plays an important role in blood clotting.

Complete solution:
The process of blood coagulation involves the transformation of circulating components in the blood into an insoluble clot. The clot forms in blood arteries and prevents blood loss. Coagulation factors, calcium, and phospholipids are required for the clotting of blood.
The coagulation factors are listed in a chronological sequence of discovery. Although there are \[13\] numbers, there are only \[12\] elements. Factor VI was later shown to be a component of another factor. Coagulation factors and their common names are as follows:
1. Fibrinogen.
2. Prothrombin.
3. Tissue thromboplastin (tissue factor)
4. Ionized calcium (\[C{a^{ + 2}}\] ).
5. Proaccelerin is a labile factor.
6. Proconvertin is a stable factor.
7. Antihemophilic factor is a protein that prevents blood from clotting.
8. A component of plasma thromboplastin.
9. Stuart prower factor.
10. Plasma thromboplastin antecedent.
11. Hageman factor and
12. Fibrin stabilizing factor.

Note:
Hepatocytes are responsible for the vast majority of clotting factors produced. Hepatocytes are responsible for producing clotting factors XIII, XII, XI, X, X, IX, VII, V, II, and I in the body. Endothelial cells produce clotting factors VIII (antihemophilic factor A) and III (tissue factor), whereas plasma contains clotting factor IV (calcium ion). Factor V is produced in part by megakaryocytes.