
Allosteric sites on an enzyme are:
A. Those other than drug-active sites
B. Those which change the shape of active sites
C. Those which don't change the shape of active sites
D. All of the above
Answer
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Hint: Enzymes are a kind of fluid that are produced by duct bearing exocrine glands. They are basically a body protein that plays the role of a catalyst in metabolic processes (such as food digestion).
Complete Answer
To find the correct answer to this question, we first need to dig a bit deeper into the concept and understand a few of the terminologies and workings of an enzyme.
Active sites: are the openings present on the substrate body through which an enzyme enters into it. It is specific for specific enzymes.
Following steps describe working of an enzyme:
1. Enzymes and substrates come together (that is, in each other's vicinity).
2. Enzyme enters into the substrate through its active site forming an enzyme-substrate complex that reduces reaction initiation energy.
3. Chemical reaction takes place between enzymes and substrates to form products. The product-enzyme complex formed. After completion of the reaction, the enzyme leaves the product to proceed alone for further reactions.
This clearly signifies that statements mentioned in both options A and B that are those other than drug-active sites and those which change the shape of active sites are correct.
Therefore, we can say that this question has two correct options, that is, A and B.
Note:
A few important terms need to be mentioned for a better understanding if the topic, such as:
Substrates: are compounds that are acted upon by an enzyme for further breakdown and conduction of metabolic processes.
Allosteric sites: are those sites that can be used to on/off or or modify the shape of the substrate, so that enzymes cannot detect it to act upon. This concept is highly used by various drugs for medical treatment.
Complete Answer
To find the correct answer to this question, we first need to dig a bit deeper into the concept and understand a few of the terminologies and workings of an enzyme.
Active sites: are the openings present on the substrate body through which an enzyme enters into it. It is specific for specific enzymes.
Following steps describe working of an enzyme:
1. Enzymes and substrates come together (that is, in each other's vicinity).
2. Enzyme enters into the substrate through its active site forming an enzyme-substrate complex that reduces reaction initiation energy.
3. Chemical reaction takes place between enzymes and substrates to form products. The product-enzyme complex formed. After completion of the reaction, the enzyme leaves the product to proceed alone for further reactions.
This clearly signifies that statements mentioned in both options A and B that are those other than drug-active sites and those which change the shape of active sites are correct.
Therefore, we can say that this question has two correct options, that is, A and B.
Note:
A few important terms need to be mentioned for a better understanding if the topic, such as:
Substrates: are compounds that are acted upon by an enzyme for further breakdown and conduction of metabolic processes.
Allosteric sites: are those sites that can be used to on/off or or modify the shape of the substrate, so that enzymes cannot detect it to act upon. This concept is highly used by various drugs for medical treatment.
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