Question

Which one of the following is not applicable for RNA?
A. Chargaff's rule
B. Complementary base pairing
C. 5' phosphoryl and 3' hydroxyl end
D. Heterocyclic nitrogenous bases

Answer 1

Hint: RNA is a ribonucleic acid synonym. In cellular processes like cell division, development, and aging, it is a nucleic acid that is central. Apart from the essence of sugar, RNA and DNA are chemically identical. It has a single helical structure and it carries essential amino acid sequence information.

Complete answer: RNA is single-stranded, RNA stands for ribonucleic acid, and Chargaff's law does not apply for RNA. In the nucleus, RNA is synthesized, but it does not exist in the nucleus. RNA replication does not take place at all. Theoretically, with the help of protein, RNA can replicate, but this does not occur. Only in a few cases does the self-replication of RNA take place. They replicate in the nucleus in the case of viroid or viruses and then pass to the organs, but this self-replication for cellular RNA is not observed. In the cytoplasm, RNA is found but, in the nucleus, it is synthesized. It is passed into the body afterward. The DNA has the genetic code that allows the code found in the RNA and RNA to make the amino acid's primary sequence to make proteins. Chargaff's law states that pyrimidine and purine bases should have a 1:1 ratio of DNA from every cell of all species (base Pair Rule), that the amount of guanine (G) is equal to cytosine (C), and that the amount of adenine (A) is equal to thymine (T). The phenomenon in which DNA guanine always bonds hydrogen to cytosine and adenine always binds to thymine is complementary base pairing. Compared to the A-T bond, which always shares two hydrogen bonds, the bond between guanine and cytosine has three hydrogen bonds. The chemical convention of naming carbon atoms in the nucleotide sugar-ring in a single strand of DNA or RNA means that there would be a 5'-end that mostly contains a phosphate group connected to the ribose ring's 5' carbon and a 3'-end Adenine (A), guanine (G), cytosine (C), and thymine (T) are four heterocyclic bases in DNA.
Thus, choice A- Chargaff's rule is the correct one.

Note: In an organism, RNA performs several roles, such as gene coding, encoding, controlling, and expressing. RNA is around 5% of a human cell's weight. DNA is made up of just about 1 percent of a cell. In both the nucleus and the cytoplasm of human cells, RNA is contained.