
Which of the following statements are correct?
(i) Failure of segregation of chromatids during cell division results in aneuploidy.
(ii) Chromosomal disorders are mainly determined by alteration or mutation in a single gene.
(iii) Thalessemia and cystic fibrosis are mendalian disorders.
(iv) Sickel cell anaemia is an X-linked trait.
(v) Haemophilia is an autosome linked recessive disease.
(A) (i) and (iii)
(B) (i), (iii) and (iv)
(C) (iii) and (iv)
(D) (ii) and (iii)
Answer
304.2k+ views
Hint: Aneuploidy is a condition of having abnormal number of chromosomes in a haploid set which can occur due to failure of segregation. Haemophilia is a X-linked disorder. Sickle cell anaemia is an autosomal recessive trait.
Complete Step by Step Answer:
Genetic abnormalities, including various birth defects in humans, are frequently caused by an extra or missing chromosome. When the chromosomes do not properly divide between the two cells during cell division, aneuploidy develops. Multiple genes may have mutations that cause chromosomal abnormalities. A genetic locus-specific mutation causes mendelian diseases. Mendelian illnesses include thalassemia and cystic fibrosis because they are caused by changes or mutations in just one gene. Because the gene is not connected to a sex chromosome, sickle cell anemia is inherited as an autosomal recessive disease. This indicates that both male and female children can inherit the gene from a parent who carries it. Haemophilia is a X-linked disease. The ability of the blood to clot is impaired by an uncommon condition known as hemophilia. Usually, it runs in the family. Men make up the bulk of those who have it. Blood that has been cut typically contains substances called clotting factors, which when combined with platelets, cause the blood to become sticky and form a clot.
So, option (A) is the correct answer.
Note: Aneuploidy is when a cell has an abnormally high number of chromosomes. In this instance, there is one additional chromosome. A cell is said to be polyploid if it has an extra set of chromosomes. A completely new set of chromosomes is present.
Complete Step by Step Answer:
Genetic abnormalities, including various birth defects in humans, are frequently caused by an extra or missing chromosome. When the chromosomes do not properly divide between the two cells during cell division, aneuploidy develops. Multiple genes may have mutations that cause chromosomal abnormalities. A genetic locus-specific mutation causes mendelian diseases. Mendelian illnesses include thalassemia and cystic fibrosis because they are caused by changes or mutations in just one gene. Because the gene is not connected to a sex chromosome, sickle cell anemia is inherited as an autosomal recessive disease. This indicates that both male and female children can inherit the gene from a parent who carries it. Haemophilia is a X-linked disease. The ability of the blood to clot is impaired by an uncommon condition known as hemophilia. Usually, it runs in the family. Men make up the bulk of those who have it. Blood that has been cut typically contains substances called clotting factors, which when combined with platelets, cause the blood to become sticky and form a clot.
So, option (A) is the correct answer.
Note: Aneuploidy is when a cell has an abnormally high number of chromosomes. In this instance, there is one additional chromosome. A cell is said to be polyploid if it has an extra set of chromosomes. A completely new set of chromosomes is present.
Recently Updated Pages
Master Class 12 Business Studies: Engaging Questions & Answers for Success

Master Class 12 Economics: Engaging Questions & Answers for Success

Master Class 12 English: Engaging Questions & Answers for Success

Master Class 12 Maths: Engaging Questions & Answers for Success

Master Class 12 Social Science: Engaging Questions & Answers for Success

Master Class 12 Chemistry: Engaging Questions & Answers for Success

Trending doubts
Why is there a time difference of about 5 hours between class 10 social science CBSE

1 ton equals to A 100 kg B 1000 kg C 10 kg D 10000 class 11 physics CBSE

Give 10 examples for herbs , shrubs , climbers , creepers

Difference Between Plant Cell and Animal Cell

How many millions make a billion class 6 maths CBSE

The aviation fuel used in the engines of jet airplanes class 10 physics CBSE
