Question

Which of the following medical conditions are responsible for producing incorrect Alpha-fetoprotein(AFP) screening results and indicating a fetus has genetic defects?
A. The mother is anaemic
B. The mother has Rh-negative blood
C. The date of conception has been miscalculated
D. All the above

Answer 1

Hint:
An AFP blood test is used to determine a pregnant woman's risk for birth abnormalities and genetic diseases such as Down syndrome and neural tube defects. The examination does not make any medical diagnoses. High levels of AFP can indicate noncancerous liver illnesses such as cirrhosis and hepatitis as well as cancers of the testicles, ovaries, or liver.
A positive AFP PLUS test places you in a higher risk category for giving birth to a child who has a chromosomal or neural tube problem. However, it does not demonstrate on its own that the pregnancy is flawed in any way. High AFP levels could be an indicator of various cancers such as Hodgkin's disease, lymphoma, or renal cell carcinoma (kidney cancer). Some patients with these tumors won't have increased AFP levels.

Complete answer:
The surface of the red blood cells also contains a protein known as Rh. Rh-positive blood indicates that you have the Rh protein, whereas Rh-negative blood indicates that you do not. Your blood type is determined by the Rh and the letter of your blood group. Alpha-fetoprotein (AFP) test results from the mother's Rh-negative blood issues are falsely positive, suggesting that the fetus has genetic abnormalities. So, the mother who has an Rh-negative blood condition is responsible for producing AFP screening results.

Option ‘B’ is correct

Note:
High levels of AFP can indicate noncancerous liver illnesses such as cirrhosis and hepatitis as well as cancers of the testicles, ovaries, or liver. Both high and normal AFP levels do not always indicate the presence of malignancy.
This examination determines the amount of AFP in your blood. When liver cells are regenerating, AFP is created. AFP may be persistently high in conditions like cirrhosis and hepatitis that affect the liver.