Question

Which of the following genotypes and phenotypes in man is the correct result of aneuploidy in sex chromosomes?
A. 22 pairs + XY females
B. 22 pairs + Y females
C. 22 pairs + XXXY females
D. 22 pairs + XXY females

Answer 1

Hint:
Aneuploidy is a condition in which the number of chromosomes is abnormal. For example, humans have 46 chromosomes. But in the case of aneuploidy, it may be 47 or 45. A genetic error can cause this to happen at any time during life, but it is more likely to occur if the number of chromosomes a child inherits from their biological parents doesn't equal 46. If there is an extra chromosome it is called trisomy and if there is a lack of a single chromosome it is called monosomy.

Complete step by step answer:
Humans have 22 pairs of somatic chromosomes and two sex chromosomes. Sex chromosomes determine your baby's sex identity at birth. The X and Y chromosomes determine a person's gender (XX for a female and XY for a male). Having only one X chromosome instead of a pair is known as Turner syndrome or monosomy X.
In a male's genetic code, there's an extra X chromosome known as Klinefelter syndrome. They have 47 chromosomes instead of 46 - two copies of the X chromosome and one copy of the Y chromosome (47, XXY).
Genes that determine maleness are expressed when one Y chromosome has a functioning SRY gene. As a result, only males are affected by XXXY syndrome. A male with XXXY syndrome has 48 chromosomes instead of 46 due to the additional two X chromosomes.

Option ‘D’ is correct

Note:
A Klinefelter syndrome occurs when the genetic code contains an extra X chromosome. There are three ways in which this can occur before birth: an extra X chromosome can be found in sperm cells, an extra X chromosome can be found in egg cells, or cells can divide incorrectly in the fetal development process (called mosaic Klinefelter syndrome).