Question

Which of the following are not produced as transgenic animals?
A. Sheep and Pig
B. Rat and Rabbit
C. Dog and Banded Krait
D. Cow and Fish

Answer 1

Hint: A transgenic animal are those animals in which the genome has been changed by the transfer of a gene or genes from another species or breed. Transgenic Organisms are those that have altered genomes most transgenic organisms are generated in the laboratory for research purposes. For example knock-out mice are transgenic.

Complete answer:
Genetically modified animals are those animals that have been genetically modified for a different kind of purposes which includes
1. Producing drugs
2. Enhancing yields
3. Increasing resistance to disease
The process of genetically engineering mammals or transgenic animals is a slow, tedious, and expensive process.

As with other genetically modified organisms (GMOs), firstly genetic engineers must isolate the gene which they want to insert into the host organism.
This can be taken from a cell containing the gene or artificially synthesised gene.
If the chosen gene or the donor organism's genome has been well studied it can easily be accessible from a genetic library.

The gene is then combined with other genetic elements which include a promoter region and terminator region and usually a selectable marker.
There are a number of techniques available for inserting the isolated gene into the host genome.

The first transgenic animals were produced by injecting viral DNA into embryos and then implanting the embryos in females.
Sheep, pig, rats, rabbit, cow and fish are transgenic animals.

So, according to the question, Dog and Banded Krait are not transgenic animals.
Hence, the correct answer is option (C).

Note: The first genetically modified animal to be commercialised was the GloFish, a Zebra fish with a fluorescent gene added that allows it to glow in the dark under ultraviolet light. It was released to the US market in 2003. The first genetically modified animal to be approved for food use was AquAdvantage salmon in 2015.