Question

What is the full form of TCT?

Answer 1

Hint: The full form of TCT may differ depending on the field of study. Calcitonin is a hormone that is responsible for lowering levels of calcium and phosphate in the blood, which aids in bone formation.

Complete answer:
There are two types of bone cells: osteoblasts and osteoclasts, which work on the formation and wear out of bone cells on a regular basis.
Thyrocalcitonin aids in the production of bone cells and wears them out.

Calcitonin, also known as thyrocalcitonin, is a protein hormone that is synthesised and secreted primarily by parafollicular cells (C cells) in the thyroid gland in humans and other mammals.

Calcitonin is secreted by cells of the glandular ultimobranchial bodies in birds, fish, and other nonmammalian vertebrates. When the calcium concentration in the blood rises above the normal level, calcitonin has the overall effect of lowering it. When phosphorus levels in the blood exceed normal, it lowers the concentration.

Calcitonin reduces serum calcium concentrations in a variety of ways. It, for example, inhibits the activity of osteoclasts in bone tissue, preventing bone resorption (breakdown), and inhibits calcium reabsorption by kidney cells, resulting in increased calcium excretion in the urine.

Calcitonin's effects counteract the effects of parathyroid hormone (parathormone), a substance secreted by the parathyroid glands that acts to raise serum calcium concentrations.

Calcitonin levels may also be elevated in patients with lung cancer and certain pancreatic tumours, such as insulinoma (an insulin-secreting tumour) and VIPoma (a vasoactive intestinal polypeptide-secreting tumour).

In biological terms the full form of TCT is Thyrocalcitonin.

Note: Synthetic calcitonin analogues are particularly interesting in the treatment of osteoporosis, a disease characterised by bone thinning caused by increased bone resorption or decreased bone formation. The calcitonin protein in humans is made up of 32 amino acids.