Courses
Courses for Kids
Free study material
Offline Centres
More
Store Icon
Store
seo-qna
SearchIcon
banner

Trypsinogen is activated by
A. HCl
B. Enterokinase
C. Bile
D. Chymotrypsin

Answer
VerifiedVerified
502.2k+ views
like imagedislike image
Hint: Trypsinogen is the precursor form of trypsin, which is a digestive enzyme. It is produced by the pancreas of the body and found in pancreatic juices which also include lipase, amylase and chymotrypsinogen. It is activated to trypsin by enteropeptidase which is found in the intestinal mucosa.

Complete answer:
Trypsinogen is a component of pancreatic juice which is composed of various digestive enzymes like chymotrypsinogen, elastase, pancreatic lipase, nucleases, carboxypeptidase, trypsinogen and amylase. These juices help in breakdown of the food into simpler form which can be absorbed by the cells of the body. Each enzyme has its own function as these are responsible for breakdown of various proteins, fats and carbohydrates.
Trypsinogen is a precursor form of trypsin which helps in breakdown of proteins into simple forms. It helps in breakdown of peptide bonds of basic amino acids so that the protein molecules can be digested. When the trypsin enzyme is inactive it is called trypsinogen and activated by another enzyme enteropeptidase which is also called enterokinase. Enterokinase is produced by the duodenum which is found in the intestinal mucosa. It helps in conversion of trypsinogen to trypsin. Trypsin also cleaves the peptide bond after lysine or an arginine, it can also cleave other trypsinogen which lead to an autocatalytic activation process.

Hence, the correct option is B. Enterokinase.

Note: Trypsin is stored in its inactivated form trypsinogen which helps it to only activate at the appropriate location. As if the trypsin is activated prematurely can be destructive and can lead to pancreatic self-digestion. Only 5% of the total trypsinogen gets activated into trypsin.
Latest Vedantu courses for you
Grade 11 Science PCM | CBSE | SCHOOL | English
CBSE (2025-26)
calendar iconAcademic year 2025-26
language iconENGLISH
book iconUnlimited access till final school exam
tick
School Full course for CBSE students
PhysicsPhysics
ChemistryChemistry
MathsMaths
₹41,848 per year
Select and buy