Question

What is true for monoclonal antibodies?
A. These antibodies obtain from one parent and for one antigen.
B. These obtain from different parents and for one antigen.
C. These obtain from one parent and for different antigens.
D. These obtain from many parents and for many antigens.

Answer 1

Hint: Monoclonal antibodies are the antibodies that are made up of identical immune cells of the body which also have the same parent cells.

Complete answer: 1: Monoclonal antibodies are the antibodies that are designed to bound only the specific single epitope but with the help of biotechnology engineering, it can be attached to the two epitopes.
2: If we manufacture the monoclonal antibodies for any substance then we can also use it for the detection of that substance later because monoclonal antibodies bodies are specific for a given substance.
3: It is also used in Western blotting for the identification of protein and also in immune dot blotting.
4: Scientists use the slides of the cells that make the monoclonal antibodies and culture them in the lab in large numbers. A large number of monoclonal antibodies can be obtained in the lab by proper culturing methods.
5: After the invention of monoclonal antibodies researchers want to develop all human products from it to reduce the chance of side effects and other casualties.
6: These are mainly used for the autoimmune diseases like rheumatoid arthritis, corn diseases, ulcerative colitis. It also helps in the organ transplantation as it inhibits the human immunoglobulin.
Hence also from the name of the antibody monoclonal means which originated from the single parent cells and also work on the single epitope.

So the correct answer is A. Monoclonal antibodies are obtained from one parent and have one antigen.

Note: 1: The first monoclonal antibody was produced in 1986 to avoid the rejection of the transplanted organ.
2: Anti CD-3 mouse antibody is used to avoid rejection.