Question

tRNA recognises ribosome by:
A. T psi C loop
B. DHU loop
C. Anticodon loop
D. AA-site

Answer 1

Hint: In reality, the tRNA molecule has three hairpin loops that resemble three leaves of a clover. Three loops in tRNA are T psi C loop, DHU loop and Anticodon loop. In order to establish a tRNA-ribosome complex during protein biosynthesis or translation, the tRNA molecule has a particular section called the T-arm or T-loop that serves as a unique recognition site for the ribosome.


Complete step by step solution:
The tRNAs for each amino acid are unique. None of the tRNAs recognize stop codons. The tertiary structure of tRNA resembles an inverted "L" shape, whereas the secondary structure is shaped like a clover leaf. As a result of hydrogen bonds forming between complementary bases, the folded structure is created. The design is also referred to as a hairpin or a hairpin loop.
A double helix with an unpaired loop is created when two portions of the same strand, which are typically complementary in nucleotide sequence when read in opposing directions, base pair. The anticodon recognizes the codon by base pairing because it has three nucleotides that are complementary to those of the corresponding codon.
The amino acid is transferred to the free 3′ end of the tRNA at the acceptor stem. The base dihydrouridine, for which the arm is named, is present in the D loop. The recognition process is the primary purpose of the D loop. The aminoacyl-tRNA synthetase enzyme, which is involved in the aminoacylation of the tRNA molecule, is thought to use it as a recognition site. It is generally accepted that the T-loop, a frequently occurring five-nucleotide motif, plays a significant role in stabilizing the tertiary RNA structure by allowing long-range interactions between various sections of the molecule. The t-loop or T psi C loop helps tRNA to recognize ribosomes.
So, option (A) is correct.

Note:
It is generally accepted that the T-loop, a frequently occurring five-nucleotide motif, plays a significant role in stabilizing the tertiary RNA structure by facilitating long-range interactions between various regions of the molecule.