Question

This type of thalassemia disease is Cooley anaemia
A. Alloimmunization
B. Beta-thalassemia
C. Alpha-thalassemia
D. None of these

Answer 1

Hint:
One of the prevalent monogenic inherited haemoglobin disorders is thalassemia major, also known as Cooley anaemia. It happens because the process of making haemoglobin does not include a beta-globin chain. Changing demographics have made it a global public health concern today.
Homozygous thalassemia, also known as Cooley anaemia or thalassemia major, is characterised by severe anaemia, spleen enlargement, and skeletal malformations. Constant Spring, Cooley's Anemia, and haemoglobin Bart hydrops fetalis are a few of the other names for thalassemias that are occasionally used. These names are unique to particular thalassemias; for example, beta thalassemia major is also known as Cooley's anaemia.

Complete answer:
You'll have minor symptoms and indicators if one gene is altered, thalassemia minor, also known as beta-thalassemia, is this condition. Your indications and symptoms will range from mild to severe due to two faulty genes. Thalassemia major, often known as Cooley anaemia, is the name of this illness These examinations may reveal whether you are a carrier and may convey the condition to your offspring through a thorough blood count (CBC). This examination measures the size, quantity, and maturity of certain blood cells in a predetermined amount of blood.
So, Beta-thalassemia is the type of thalassemia disease which is Cooley anaemia.

Option ‘B’ is correct

Note:
Hemoglobin synthesis is decreased by the blood condition beta-thalassemia. The protein in red blood cells called haemoglobin, which contains iron, transports oxygen to all of the body's cells. Low haemoglobin levels in beta-thalassemia patients cause an oxygen shortage in several bodily regions. Major complications from beta thalassemia can lead to early mortality. Delay in growth, bone issues that result in facial alterations, liver and gall bladder issues, an enlarged spleen, an enlarged kidney, diabetes, hypothyroidism, and heart issues are possible complications.
Hemoglobin beta (HBB) gene mutations are the primary cause of beta-thalassemia. While both HBB genes are mutated in the intermediate and major types of beta thalassemia, only one HBB gene is mutated in the minor form.