Question

This about beta-thalassemia is true
A. two genes are necessary to make beta-globin chains
B. Mutation of genes decides the severity of the condition
C. Beta thalassemia is a common condition in West Asia, North Africa, and the Mediterranean islands
D. All of these

Answer 1

Hint:
Before answering the question, we should know the basic information about beta-thalassemia.
Hemoglobin synthesis is decreased by the blood condition beta-thalassemia. The protein in red blood cells called haemoglobin, which contains iron, transports oxygen to all of the body's cells. Low haemoglobin levels in beta-thalassemia patients cause an oxygen shortage in several bodily regions. Major complications from beta thalassemia can lead to early mortality. Delay in growth, bone issues that result in facial alterations, liver and gall bladder issues, an enlarged spleen, an enlarged kidney, diabetes, hypothyroidism, and heart issues are possible complications.

Complete answer:
Hemoglobin beta (Hb-B) gene mutations are the primary cause of beta-thalassemia. While both Hb-B genes are mutated in the intermediate and major types of beta-thalassemia, only one Hb-B gene is mutated in the minor form. The spongy tissue found in the center of some bones called bone marrow is where stem cells are created. These cells have the capacity to differentiate into several blood cell types.
So, all of the above statements are true.

Option ‘D’ is correct

Note:
Thalassemia is a dangerous medical disorder that can have a considerable influence on a person's life, even though the main health issues it causes can frequently be treated. There is still a chance that you could pass on a more dangerous type to your offspring, even in moderate situations. Worldwide, beta-thalassemia is a rather prevalent blood condition. Each year, thousands of newborns with beta-thalassemia are delivered.