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The karyosome of Entamoeba histolytica is
A. Liver
B. Progressive
C. Central
D. Even

Answer
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Hint:
Entamoeba histolytica/Entamoeba dispar cysts are mature when they have four nuclei, each of which has fine, uniformly distributed chromatin in the periphery and centrally positioned karyosomes. When a cell is not going through meiotic division, the term "karyosome" refers to the chromatin content inside the cell nucleus. It looks like a large, dense mass in the cell's center and is frequently confused with the nucleolus. For its function in oogenesis, the karyosphere or karyosome is particularly well-known.
Entamoeba histolytica life cycle. After being consumed, the cyst form travels from the mouth to the small intestine, where excystation takes place. The cyst divides into eight trophozoites during excystation by going through nuclear, followed by cytoplasmic, division. These trophozoites subsequently go to the big bowel.

Complete answer:
Anaerobic parasite Entamoeba histolytica is often located in the colon, but for unknown reasons, it has the ability to become invasive, break the gut barrier, and move toward the liver, where it can cause amoebic liver abscesses. When cysts are consumed by contaminated food or water, E. histolytica infections develop. Cysts in the lower intestine give rise to trophozoites (a process known as excystation).
So, the karyosome of Entamoeba histolytica is central.

 Option ‘C’ is correct

Note:
Entamoeba histolytica have a single, spherical or oval-shaped nucleus with a distinct nuclear border, a central karyosome, and a vacuole. They also have a thin cell membrane. They go toward the colon on finger-like pseudopods. To survive, trophozoites consume red blood cells and absorb their resources. The protozoan parasite Entamoeba histolytica (Eh) interacts dynamically with the host intestinal epithelium throughout disease development and is the cause of intestinal amebiasis.
The parasitic anaerobic amoebozoan Entamoeba histolytica belongs to the genus Entamoeba. E. histolytica, which mostly infects humans and other primates and causes amoebiasis, is thought to infect between 35 and 50 million individuals worldwide.