Question

The gene responsible for causing Duchenne muscular dystrophy is found on
A. Y chromosome
B. X chromosome
C. Autosomal chromosome number 5
D. Autosomal chromosome number 8

Answer 1

Hint:
Before we proceed into the problem, it is important to know the definitions of Duchenne muscular dystrophy.
The most prevalent form of several pediatric muscular dystrophies, it manifests before the age of six years and is a hereditary condition (X-linked recessive). Girls are less likely to get this disease than boys, although females might still experience some of the symptoms, such as fatigued, and weaker arms, legs, and back muscles. Some people could require a wheelchair or other mobility devices. Carriers may have shortness of breath, cardiac issues, and a failure to engage in mild exercise. If left unaddressed, heart issues might become very serious and even fatal.

Complete answer:
The gene responsible for causing Duchenne muscular dystrophy is found on the X chromosome. This means that men are more likely to get this condition than women, and sons are typically affected more severely than daughters. While there is no cure available for DMD, there are treatments available that can help improve symptoms.
Some of the most common treatments include neural tube surgery to alter or remove defective muscles, physiotherapy and occupational therapy to help with movement skills and motor function, medications such as steroids or beta-agonists (drugs used to treat asthma), and gene therapy. However, even with treatment it usually results in a slow decline over time due to muscle loss.
Therefore, the gene responsible for causing Duchenne muscular dystrophy is found on the X chromosome.

Option ‘B’ is correct

Note:
Chromosomes are rod-shaped structures that are easily visible in the cell during cell division. They are DNA molecules with a high degree of supercoiling that stay coiled around histone and non-histone proteins. With 155 million DNA base pairs, the X chromosome makes up 5% of the DNA in a cell. The X chromosomes contain between 800 and 900 genes in total.