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The complications that can occur in severe thalassemia is
A. Enlarged spleen
B. Bone deformities
C. Problems with the heart
D. All of these

Answer
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Hint:
A genetic blood condition called thalassemia results in the body producing less haemoglobin than typical. Red blood cells can carry oxygen because haemoglobin is present. Anaemia brought on by thalassemia can make you feel exhausted.
You might not need therapy if you have mild thalassemia. However, more serious conditions could need frequent blood transfusions. You can take action to deal with exhaustion by following a nutritious diet and doing frequent exercise.

Complete answer:
Bone anomalies: Your bone marrow may enlarge as a result of thalassemia, which will widen your bones. Your face and skull, in particular, may have an aberrant bone structure as a result of this. Additionally, bone marrow enlargement thins and renders bones fragile, raising the risk of broken bones.
Expanded spleen: Your body uses the spleen to filter undesired substances like stale or damaged blood cells and combat infection. Red blood cell apoptosis is frequently a complication of thalassemia. Your spleen grows and has to work more than usual as a result.
An enlarged spleen can shorten the lifespan of transfused red blood cells and exacerbate anaemia. If your spleen becomes too large, your doctor may advise having it surgically removed.

Option ‘D’ is correct

Note:
Beta thalassemia, a blood condition, can lead to issues like cardiac issues, delayed growth in children, and bone damage. You or your child may be able to prevent many of these issues with treatment. Haemoglobin production in the body is decreased by beta-thalassemia. Red blood cells provide oxygen to your organs and tissues with the help of haemoglobin.