Question

State the best known contribution of
A. Alec Jeffery
B. P.K Sethi
C. Hugo de Vries

Answer 1

Hint: Alec Jeffry is famous for his work in DNA fingerprinting. PK Sethi is a world-known inventor for the most affordable artificial limb known as ‘Jaipur foot’. Hugo De Vries is recognized for his valuable suggestion of the concept of the gene.

Complete answer:
A. Alec Jeffreys: He was a British geneticist who developed techniques for DNA fingerprinting and DNA profiling. The current forensic science involving Genetic fingerprinting in assistance to police work is based on Sir Alec John Jeffreys's contribution.

B. PK Sethi: Pramod Karan Sethi was a well-known Indian Orthopaedic surgeon. He developed prosthetic limbs made up of rubber and wood. It is the lowest cost of prosthetic limbs available in the world. This prosthetic limb is called the Jaipur foot. He was awarded one of the most prestigious awards, Padma Shri by the Indian government in 1969 for his contribution to science.

C. Hugo de Vries: He is known as one of the first Geneticists in the world. He was a Dutch botanist who presented mutation theory and the importance of mutations in evolution.

Additional information:
DNA fingerprinting is used to match DNA samples from the area of collection and DNA sample of the suspect of a crime. Four main steps are extraction, quantification, amplification, and capillary electrophoresis. DNA profiling is also used for the same purpose as DNA fingerprinting but instead of using restriction enzymes for cutting of DNA, it uses PCR to produce multiple copies of specific STR sequences.

Note: Jaipur foot by PK Sethi and mutation theory by Hugo de Vries. Jaipur foot is a prosthetic limb for people with below-knee amputation which makes it easy for people to walk, run, and cycle, and in performing other physical limb activities
Mutation theory states that sudden alteration in genes is the driving force of evolution. Mutations are referred to as discontinuous variations.